Intramural adenocarcinoma of the uterus, arisen from adenomyosis uteri, showing unique histologic appearances. Report of two cases.

Kuwashima Y, Y Kuwashima, T Uehara, Tomoko Uehara, Uehara T, Kishi K, Katsuyuki Kishi, K Kishi, Hiroyuki Tajima, H Tajima, Tajima H, Shiromizu K, K Shiromizu, M Matsuzawa, Matsuzawa M, Masumi Matsuzawa, S Takayama, Takayama S
European journal of gynaecological oncology · 1994 · vol. 15(6) , pp. 418–23 · PMID:7875156 · W2418541348
article OA: closed CC0 ⤵ 8 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This paper reports two cases of intramural uterine adenocarcinoma arising from adenomyosis, demonstrating diverse histological features including papillary formations and mimicking benign adenomyosis.

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Abstract

Two cases of uterine adenocarcinoma which grew mainly in myometrium and showed unique histologic appearances are reported. Both cases were considered to have arisen from adenomyosis uteri because transitional figures were observed between carcinoma cells and adenmyotic glands in one case, and carcinomatous glands were scattered in myometrium and were associated with endometrial stroma which mimicked benign adenomyosis in another. The former case was poorly differentiated adenocarcinoma and the latter was well-differentiated adenocarcinoma. Interestingly, in the latter case, the carcinoma cells were transformed into papillary adenocarcinoma such as has been observed in the thyroid gland, and formed well-demarcated nodular mass. These findings indicate that adenocarcinoma which arise from adenomyosis uteri could show various histologic appearances, in addition to usual endometrioid adenocarcinoma.

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Condition tags

endometriosisadenomyosis

MeSH descriptors

Adenocarcinoma Uterine Neoplasms Adenocarcinoma Cell Transformation, Neoplastic Endometriosis Endometriosis Fatal Outcome Female Humans Middle Aged Myometrium Myometrium Uterine Diseases Uterine Diseases Uterine Neoplasms Vaginal Smears

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (8)

Source provenance

europepmc
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License: CC0 · commercial use OK