Comparing Interleukin 10 (IL-10) Level in Women with Adenomyosis and without Adenomyosis

Dewi Eka Satria; John Rambulangi; Deviana Soraya Riu; Maisuri Tadjuddin; Nusratuddin Abdullah; Trika Irianta

doi:10.3923/rjog.2019.28.32

Comparing Interleukin 10 (IL-10) Level in Women with Adenomyosis and without Adenomyosis

Dewi Eka Satria, John Rambulangi, Deviana Soraya Riu, Maisuri Tadjuddin, Nusratuddin Abdullah, Trika Irianta

In: Research Journal of Obstetrics and Gynecology · 2019 · vol. 12(1) , pp. 28–32 · doi:10.3923/rjog.2019.28.32 · W2954791682

article OA: diamond CC0 ⤵ 1 in-corpus citation

🔓 Open OA copy Full text JSON View on OpenAlex View at publisher

⚙ AI-generated summary by claude@2026-06, 2026-06-12 ⓘ

This study found that women with adenomyosis had significantly higher levels of interleukin 10 compared to women without adenomyosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text ⓘ

This paper compared Interleukin-10 (IL-10) levels in women diagnosed with adenomyosis versus women without adenomyosis, using a case–control approach recruited from an obstetrics and gynecology setting in Indonesia. The central finding was that IL-10 levels differed between the two groups, indicating an association between IL-10 and adenomyosis status. The main limitation is that the information provided does not specify the sample size, assay methods, or whether potential confounders (such as inflammatory conditions or medication use) were controlled, which affects interpretability. This paper is centrally about adenomyosis — it specifically compares IL-10 levels in women with and without adenomyosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Background and Objective: Adenomyosis is a disease characterized with heterotrophic stromal and endometrial glands within myometrium surrounded by myometrium hyperplasia. Alterations of immunological system contributed in adenomyosis pathogenesis. One of the cytokines role in adenomyosis pathophysiology is IL-10. This research aimed to investigate the comparison of IL-10 in women with adenomyosis and without adenomyosis. Materials and Methods: The research was conducted at Wahidin Sudirohusodo General Hospital and at the network hospitals using the nested case control method. The samples were 37 women with adenomyosis and diagnosed based on the histopathology results and 37 women without adenomyosis. The levels of IL-10 were measured using ELISA method. The data were analyzed using Chi-square test, Mann-Whitney test and Spearman correlation test with the significance of p = 0.05. Results: The finding of this study indicated that the levels of IL-10 in women with adenomyosis were higher compared to the women without adenomyosis (p = 0.001). IL-10 levels has a weak correlation with the incidence of adenomyosis and medium correlation with the size of adenomyosis. Conclusion: So it was concluded that there was increased levels of IL-10 in adenomyosis patients compared with no adenomyosis.

Full text 1,274 characters · extracted from oa-doi-fallback · click to expand

Dewi Eka Satriani Department of Obstetrics and Gynaecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia LiveDNA: 62.27202 John Rambulangi Department of Obstetrics and Gynaecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Deviana Soraya Riu Department of Obstetrics and Gynaecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Maisuri Tadjuddin Chalid Department of Obstetrics and Gynaecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Nusratuddin Abdullah Department of Obstetrics and Gynaecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia Trika Irianta Department of Obstetrics and Gynaecology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia PDF Fulltext XML References Citation How to cite this article Dewi Eka Satriani, John Rambulangi, Deviana Soraya Riu, Maisuri Tadjuddin Chalid, Nusratuddin Abdullah and Trika Irianta, 2019. Comparing Interleukin 10 (IL-10) Level in Women with Adenomyosis and without Adenomyosis. Research Journal of Obstetrics and Gynecology, 12: 28-32. DOI: 10.3923/rjog.2019.28.32 URL: https://scialert.net/abstract/?doi=rjog.2019.28.32 DOI: 10.3923/rjog.2019.28.32 URL: https://scialert.net/abstract/?doi=rjog.2019.28.32

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works