True osseous metaplasia of the endometrium: the bone is not from a fetus

E. Cayuela, Enrique Cayuela, Tirso Pérez‐Medina, Tirso Perez-Medina, Joan C. Vilanova, Joan Vilanova, Maria Alejo, María Alejo, M. Paz Cañadas, Paz Cañadas
Fertility and sterility · 2009 · vol. 91(4) , pp. 1293.e1–1293.e4 · doi:10.1016/j.fertnstert.2008.12.026 · PMID:19185859 · W2009057866
Case report OA: bronze CC0 ⤵ 23 in-corpus citations
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This report describes a case of true osseous metaplasia of the endometrium, confirming the bone formation originated from the mother and not from a fetus.

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Abstract

OBJECTIVE: To identify the origin of calcified tissue in endometrial ossification. DESIGN: DNA analyses from the ossified tissue and from the woman were studied to compare both genotypes. SETTING: University and general hospitals. PATIENT(S): A 27-year-old infertile woman diagnosed of osseous metaplasia of the endometrium. INTERVENTION(S): Hysteroscopic resection of the endometrial osseous metaplasia for DNA analysis. MAIN OUTCOME MEASURE(S): DNA comparison between the patient and the osseous tissue extracted from the uterus. RESULT(S): All markers produced the same allele length for both blood and endometrial biopsy (including bones), thus confirming the same genetic origin. CONCLUSION(S): Endometrial ossification is derived from the patient, resulting in a true osseous metaplasia.

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MeSH descriptors

Bone and Bones Endometrium Fetus Ossification, Heterotopic Abortion, Induced Abortion, Induced Adult Bone and Bones Bone and Bones Diagnosis, Differential Endometrium Female Fetus Fetus Genotype Humans Infertility, Female Infertility, Female Infertility, Female Metaplasia

Citation neighborhood (2-hop)

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References (13)

Cited by (16)

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