Two Unusual Presentations of Müllerian Adenosarcoma: Case Reports, Literature Review, and Treatment Considerations

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This paper presents two unusual cases of Müllerian adenosarcoma, reviews the existing literature, and discusses treatment strategies for this rare tumor.

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Abstract

Müllerian adenosarcomas of the uterus usually present as pedunculated endometrial masses in postmenopausal women with vaginal bleeding. Extraendometrial variants (originating in the ovary, adnexa, or myometrium) are much less common, and they tend to present at a more advanced stage due to their location. The sarcomatous portion of müllerian adenosarcoma can vary from low grade to very high grade and the clinical behavior of the tumors can be indolent or aggressive. We present two cases, one of which originated in the adnexa and the other in an apparent focus of uterine adenomyosis. These cases illustrate the difficulty of correct diagnosis and treatment.

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MeSH descriptors

Adenosarcoma Mixed Tumor, Mullerian Uterine Neoplasms Adenosarcoma Adenosarcoma Adult Combined Modality Therapy Female Humans Mixed Tumor, Mullerian Mixed Tumor, Mullerian Uterine Neoplasms Uterine Neoplasms

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