Resolution of catamenial epilepsy after goserelin therapy and oophorectomy: case report of presumed cerebral endometriosis

George A. Vilos, Vilos GA, Hollett-Caines J, Jackie Hollett-Caines, Basim Abu‐Rafea, Basim Abu-Rafea, Abu-Rafea B, Riad Ahmad, Ahmad R, Mazurek MF, Michel F. Mazurek
Journal of Minimally Invasive Gynecology · 2011 · vol. 18(1) , pp. 128–130 · doi:10.1016/j.jmig.2010.09.002 · PMID:21195968 · W2056162349
Case report OA: closed CC0 ⤵ 10 in-corpus citations
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This case report describes a patient with catamenial epilepsy that resolved following goserelin therapy and oophorectomy, suggesting a potential link to cerebral endometriosis.

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Abstract

Endometriosis can develop in every organ and tissue in the female body except perhaps the spleen. The mechanism of distal metastasis is thought to be hematogenous or lymphatic spread from the uterus. Endometriotic lesions in the central nervous system are rare. Herein, we report the case of a woman with abnormal uterine bleeding who developed catamenial neurologic signs and symptoms. Computed tomography scans and magnetic resonance images demonstrated a circumscribed lesion in the left centrum semiovale of the brain. All neurologic symptoms resolved completely after treatment with gonadotropin-releasing hormone agonist for 3 months and subsequent laparoscopic bilateral oophorectomy. The patient was thought to have cerebral endometriosis, a rare phenomenon, although several cases have been reported in the literature. Temporal association of neurologic signs and symptoms with menstruation that resolves with medical or surgical menopause is highly suggestive of cerebral endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Antineoplastic Agents, Hormonal Endometriosis Epilepsy Goserelin Ovariectomy Ovariectomy Antineoplastic Agents, Hormonal Antineoplastic Agents, Hormonal Endometriosis Endometriosis Endometriosis Endometriosis Epilepsy Epilepsy Epilepsy Female Female Goserelin Goserelin Humans

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

References (8)

Cited by (11)

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