Resolution of Catamenial Epilepsy after Goserelin Therapy and Oophorectomy: Case Report of Presumed Cerebral Endometriosis
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This case report describes a patient with catamenial epilepsy that resolved following goserelin therapy and oophorectomy, suggesting a potential link to cerebral endometriosis.
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Abstract
Endometriosis can develop in every organ and tissue in the female body except perhaps the spleen. The mechanism of distal metastasis is thought to be hematogenous or lymphatic spread from the uterus. Endometriotic lesions in the central nervous system are rare. Herein, we report the case of a woman with abnormal uterine bleeding who developed catamenial neurologic signs and symptoms. Computed tomography scans and magnetic resonance images demonstrated a circumscribed lesion in the left centrum semiovale of the brain. All neurologic symptoms resolved completely after treatment with gonadotropin-releasing hormone agonist for 3 months and subsequent laparoscopic bilateral oophorectomy. The patient was thought to have cerebral endometriosis, a rare phenomenon, although several cases have been reported in the literature. Temporal association of neurologic signs and symptoms with menstruation that resolves with medical or surgical menopause is highly suggestive of cerebral endometriosis.
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References (8)
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- Laparoscopic Findings, Management, Histopathology, and Outcomes in 25 Women with Cyclic Leg Pain via openalex
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- W2041424857 via openalex
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Cited by (10)
- The rarest forms of endometriosis 2022
- Psychiatric Symptoms in Patients with Cerebral Endometriosis: A Case Report and Literature Review 2022
- Extrapelvic Endometriosis Mimicking Peritoneal Surface Malignancy: Case Report and a Review of Literature 2022
- Case Report of Cerebellar Endometriosis 2020
- A surgical solution for a catamenial epilepsy medical therapy-resistant: A presumed case of cerebral endometriosis? 2020
- Extrapelvic Endometriosis: A Systematic Review 2019
- Complete remission of cerebral endometriosis with dienogest: a case report 2018
- Micrometastasis of endometriosis to distant organs in a murine model 2017
- Neural involvement in endometriosis: Review of anatomic distribution and mechanisms 2015
- Cyclic Sciatica Due to Endometriosis of the Sciatic Nerve: Neurolysis with Combined Laparoscopic and Transgluteal Approaches 2014
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- europepmc
- last seen: 2026-07-26T06:08:39.051465+00:00
- openalex
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- pubmed
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