Depth of Intestinal Wall Infiltration and Clinical Presentation of Deep Infiltrating Endometriosis: Evaluation of 553 Consecutive Cases

Rossini R, Roberto Rossini, Giorgio Lisi, Lisi G, Anna Pesci, Pesci A, Marcello Ceccaroni, Zamboni G, Giuseppe Zamboni, Irene Gentile, Gentile I, Lorenzo Rettore, Rettore L, Giacomo Ruffo, Ruffo G
Journal of laparoendoscopic & advanced surgical techniques. Part A · 2017 · vol. 28(2) , pp. 152–156 · doi:10.1089/lap.2017.0440 · PMID:29023195 · W2762512348
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This study analyzed 553 deep infiltrating endometriosis cases, finding no correlation between symptom severity and intestinal wall infiltration depth, but did find a link between submucosal infiltration and positive visceral lymph nodes.

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Abstract

INTRODUCTION: Intestinal involvement in endometriosis was first described by Sampson in 1922. The reported incidence ranges between 3% and 37% in patients diagnosed with endometriosis. In literature, there are few studies that correlate the severity of endometriosis (in terms of intestinal infiltration) and its clinical presentation. The aim of this study was to review the correlation between the severity of symptoms, the depth of intestinal wall infiltration, and lymph node involvement in our tertiary referral center. MATERIALS AND METHODS: We retrospectively analyzed 553 patients who had undergone intestinal resection for deep infiltrating endometriosis at our institution (Sacro Cuore Negrar Hospital) between 2004 and 2009. Based on intestinal wall infiltration, we divided patients into three groups (Group A: intestinal infiltration that reaches the muscle layer, Group B: infiltration to the submucosa, and Group C: endometriosis reaches the mucosa). Symptoms, intestinal stenosis, and positive lymph nodes were compared in the three groups with the chi-square test. RESULTS: No statistical correlation was found between symptoms and the intestinal wall infiltrations. The three groups were also compared on the basis of positive visceral lymph nodes and we did find a statistical difference (P = .05) in the lymph node count in the two main groups. CONCLUSION: There seems to be no statistically significant difference in symptoms between patients with different degrees of infiltration. Although visceral lymph node involvement has been occasionally described in literature, we found that it is related to submucosal infiltration.

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Condition tags

endometriosisdie_deep_infiltrating

MeSH descriptors

Endometriosis Intestinal Diseases Intestines Lymph Nodes Adult Endometriosis Endometriosis Endometriosis Female Humans Intestinal Diseases Intestinal Diseases Intestines Intestines Laparoscopy Laparoscopy Lymph Nodes Lymph Nodes Middle Aged Retrospective Studies

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