The Role of Computed Tomography Colonography in Detecting Bowel Involvement in Women With Deep Infiltrating Endometriosis

Silvia Baggio, Alessandro Zecchin, Zecchin A, Paola Pomini, Pomini P, Giovanni Zanconato, Zanconato G, Genna M, Michele Genna, Motton M, Massimiliano Motton, Stefania Montemezzi, Massimo Franchi, Massimo Piergiuseppe Franchi
Journal of computer assisted tomography · 2016 · vol. 40(6) , pp. 886–891 · doi:10.1097/rct.0000000000000447 · PMID:27841773 · W2554806280
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Computed tomographic colonography demonstrated higher accuracy in detecting bowel endometriosis compared to clinical symptoms, Ca125 levels, and transvaginal sonography in women undergoing surgery for deep infiltrating endometriosis.

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Abstract

OBJECTIVE: We wanted to assess the diagnostic value of computed tomographic colonography (CTC) in recognizing bowel endometriosis in comparison with serum Ca125, transvaginal sonography (TVS), and presence of intestinal symptoms. METHODS: We included in this study 92 women undergoing surgery for symptomatic DIE. Preoperative evaluation included clinical history, Ca125 serum value, and TVS. CTC was performed in 37/92 patients (40.2%), and the results were compared to the other preoperative tools and to surgical exploration, considered the clinical reference standard. RESULTS: Surgery confirmed bowel endometriosis in 49/92 subjects (53.3%). Presence of intestinal symptoms, serum Ca125 values, and TVS were significantly correlated to intestinal involvement, but CTC had the highest accuracy in detecting bowel endometriosis with a sensitivity of 68%, a specificity of 67%, a PPV of 81%, and a NPV of 50% (P = 0.04). CONCLUSIONS: CTC proved to be an accurate and low invasive imaging technique to detect DIE of the bowel and compared favorably with clinical evaluation, serum Ca125 determination, and TVS.

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Condition tags

endometriosisdie_deep_infiltratingbowel_endometriosis

MeSH descriptors

CA-125 Antigen Colonography, Computed Tomographic Endometriosis Endometriosis Intestinal Diseases Intestinal Diseases Membrane Proteins Adult Biomarkers, Tumor Biomarkers, Tumor CA-125 Antigen Colonography, Computed Tomographic Endometriosis Endometriosis Female Humans Intestinal Diseases Intestinal Diseases Italy Italy

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