[Detection of expression of endometriosis-related cytokine and their receptor genes by cDNA microarray technique]

Fan Y, Fan Yang, Yang Fan, Bi-liang Chen, Biliang Chen, Chen BL, Xiang-Dong Ma, Xiangdong Ma, Ma XD, Ming-quan Su, Su MQ
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology · 2005 · vol. 21(4) , pp. 489–92 · PMID:15989799 · W2393602046
Lab / animal OA: closed CC0 ⤵ 6 in-corpus citations
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This study used cDNA microarrays to find that 15 cytokine and receptor genes, including IL-1, IL-6, and VEGFR, were expressed differently in endometriosis tissues compared to normal endometrial tissues.

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Abstract

AIM: To study the pathogenesis of endometriosis(EM) by investigating cytokine(CK) and CKR genes expression involved in the development of EM. METHODS: The CK and CKR gene expression pattern in samples of EM and normal endometrial tissues were analyzed by using cDNA microarrays. RESULTS: 119 genes were expressed differently between 3 cases EM tissues and 3 cases normal endometria tissues. Among them, 15 were CK and CKR genes, including IL-1, IL-2, IL-6, IL-8, VEGFR, TGF, EGF, FGF, and EPOR etc. CONCLUSION: These 15 differently expressed CK and CKR genes may be correlated with the development of EM.

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Condition tags

endometriosis

MeSH descriptors

Cytokines Endometriosis Gene Expression Profiling Gene Expression Profiling Oligonucleotide Array Sequence Analysis Oligonucleotide Array Sequence Analysis Receptors, Cytokine Animals Animals Cytokines Cytokines Endometriosis Endometriosis Endometriosis Endometrium Endometrium Endometrium Endometrium Endometrium Female

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

Cited by (6)

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europepmc
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License: CC0 · commercial use OK