[Detection of expression of endometriosis-related cytokine and their receptor genes by cDNA microarray technique].

Fan Y, Fan Yang, Yang Fan, Bi-liang Chen, Biliang Chen, Chen BL, Xiang-Dong Ma, Xiangdong Ma, Ma XD, Ming-quan Su, Su MQ
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology · 2005 · vol. 21(4) , pp. 489–92 · PMID:15989799 · W2393602046
article OA: closed CC0 ⤵ 6 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-28 ⓘ

This study used cDNA microarrays to find that 15 cytokine and receptor genes, including IL-1, IL-6, and VEGFR, were expressed differently in endometriosis tissues compared to normal endometrial tissues.

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Abstract

AIM: To study the pathogenesis of endometriosis(EM) by investigating cytokine(CK) and CKR genes expression involved in the development of EM. METHODS: The CK and CKR gene expression pattern in samples of EM and normal endometrial tissues were analyzed by using cDNA microarrays. RESULTS: 119 genes were expressed differently between 3 cases EM tissues and 3 cases normal endometria tissues. Among them, 15 were CK and CKR genes, including IL-1, IL-2, IL-6, IL-8, VEGFR, TGF, EGF, FGF, and EPOR etc. CONCLUSION: These 15 differently expressed CK and CKR genes may be correlated with the development of EM.

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Condition tags

endometriosis

MeSH descriptors

Cytokines Endometriosis Gene Expression Profiling Oligonucleotide Array Sequence Analysis Receptors, Cytokine Animals Cytokines Endometriosis Endometriosis Endometrium Endometrium Endometrium Endometrium Female Receptors, Cytokine RNA RNA RNA RNA Software

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

Cited by (6)

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europepmc
last seen: 2026-08-06T06:07:45.168820+00:00
openalex
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pubmed
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License: CC0 · commercial use OK