A rare case of mullerianosis of the liver and lung mimicking metastatic biliary cystadenocarcinoma

Charles Panackel, Francis Mathew J, Joe Francis Mathew, John N, Nita John, Jacob M, Mathew Jacob
The journal of the Royal College of Physicians of Edinburgh · 2024 · vol. 54(2) , pp. 149–152 · doi:10.1177/14782715241247244 · PMID:38660757 · W4395463486
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This case report describes a rare instance of simultaneous liver and lung mullerianosis in a 41-year-old female, which mimicked metastatic biliary cystadenocarcinoma and was diagnosed via histopathology and immunohistochemistry.

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Abstract

Anatomically, normal cells found in an abnormal site are known as choristoma. When any two of the three-cell lineage of the mullerian duct, that is endosalpinx, endocervix and endometrium, are found at an abnormal location, it is termed mullerian choristoma or mullerianosis. Mullerianosis histologically reveals glands of varying sizes lined by cervical, tubal and endometrial cells. Individual cell lineages like endometriosis of the ovary, endosalpingiosis and endocervicosis of the urinary bladder are common. But mullerianosis is quite rare, and as per literature, only about 20 cases have been reported. We report a mullerianosis involving the liver and lung in a 41-year-old female that mimicked metastatic biliary cystadenocarcinoma. It is the first case reported in literature where there is simultaneous involvement of the liver and lung by mullerianosis. The diagnosis was made with the help of histopathology and immunohistochemistry in the resected specimens.

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Condition tags

endometriosis

MeSH descriptors

Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma Choristoma

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