Aberrant expression of keratinocyte growth factor receptor in ovarian surface epithelial cells of endometrioma

Fuminori Taniguchi; Taniguchi F; Harada T; Tasuku Harada; Iwabe T; Tomio Iwabe; Ohama Y; Yoko Ohama; Yasuko Takenaka; Takenaka Y; Naoki Terakawa; Terakawa N

doi:10.1016/j.fertnstert.2007.02.060

Aberrant expression of keratinocyte growth factor receptor in ovarian surface epithelial cells of endometrioma

Fuminori Taniguchi, Taniguchi F, Harada T, Tasuku Harada, Iwabe T, Tomio Iwabe, Ohama Y, Yoko Ohama, Yasuko Takenaka, Takenaka Y, Naoki Terakawa, Terakawa N

Fertility and sterility · 2007 · vol. 89(2) , pp. 478–480 · doi:10.1016/j.fertnstert.2007.02.060 · PMID:17482184 · W1972688129

article OA: bronze CC0 ⤵ 2 in-corpus citations

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This study investigated the expression of keratinocyte growth factor receptor in ovarian surface epithelial cells from women with endometrioma and found it to be aberrantly expressed.

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Abstract

Ovarian surface epithelial cells (OSEs) are considered to be the common source of endometrioma and epithelial ovarian cancer. The present study reveals that keratinocyte growth factor receptor (KGFR) messenger RNA was expressed in OSEs of endometriomas but not in those of normal ovaries, suggesting that autocrine KGF/KGFR and paracrine fibroblast growth factor 10/KGFR signaling loops may be involved with the proliferation in OSEs of endometrioma.

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Condition tags

endometriosisendometrioma

MeSH descriptors

Endometriosis Epithelial Cells Ovarian Diseases Ovary Receptor, Fibroblast Growth Factor, Type 2 Cells, Cultured Endometriosis Endometriosis Epithelial Cells Female Gene Expression Regulation Humans Ovarian Diseases Ovarian Diseases Ovary Receptor, Fibroblast Growth Factor, Type 2 Receptor, Fibroblast Growth Factor, Type 2

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Too few in-corpus citations on either side for a chart; here are the lists.

Cites (2)

Cited by (2)

References (13)

Classification of Ovarian Endometriotic Cysts via openalex
Large ovarian endometriomas via openalex
doi:10.1111/j.1471-0528.1957.tb06276.x via openalex
doi:10.1038/sj.onc.1204755 via openalex
doi:10.1210/endo.139.1.5680 via openalex
doi:10.1210/endo.142.1.7862 via openalex
doi:10.1210/jc.2002-021062 via openalex
doi:10.1074/jbc.273.21.13230 via openalex
doi:10.1016/s0015-0282(16)53160-4 via openalex
doi:10.1016/s0015-0282(01)01747-2 via openalex
doi:10.1016/s0303-7207(00)00284-7 via openalex
doi:10.1095/biolreprod49.3.635 via openalex
doi:10.1016/s0015-0282(16)56752-1 via openalex

Cited by (2)

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[1] Large ovarian endometriomas 1996

[2] Classification of Ovarian Endometriotic Cysts 2001