Endometriosis en Chile: Un análisis de la cargahospitalaria y las tendencias de egresos entre2020 y 2023

Camila Gomez, Carlos Gegúndez Gómez
In: Revista ANACEM · 2025 · vol. 19(1) · doi:10.70536/revanacem/v19n1-202579 · W4414029025
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This study found that the hospital discharge rate for endometriosis in Chile increased in 2023, was highest in women aged 20-44, and most frequently involved uterine endometriosis.

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This observational descriptive quantitative study used Chilean health administrative data from DEIS and population data from INE to characterize the hospital discharge rate of endometriosis from 2020 to 2023, summarizing trends with descriptive statistics in Excel. The highest rate occurred in 2023 (64.15 per 100,000 inhabitants), with the greatest discharge rate in women aged 20–44 years (82.90 per 100,000), and uterine endometriosis accounting for 50.55% of cases. The authors note limitations inherent to administrative/discharge data and propose that the rise may reflect increased interventions, while higher uterine proportions may relate to greater diagnostic accessibility compared with other or unspecified locations. This paper is centrally about endometriosis — it quantifies and analyzes Chilean hospital discharge trends for endometriosis between 2020 and 2023.

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Abstract

Resumen Introducción: La endometriosis es una enfermedad inflamatoria crónica caracterizada por la presencia de tejido endometrial fuera de la cavidad uterina. Objetivo: Describir la Tasa de Egreso Hospitalario (TEH) de endometriosis durante el periodo 2020 a 2023 en Chile. Materiales y métodos: Estudio observacional, descriptivo y cuantitativo con datos estadísticos del Departamento de Estadística e Información de Salud (DEIS) y del Instituto Nacional de Estadística (INE). Se utilizaron medidas de tendencia central con apoyo de gráficas y tablas con software analítico Excel. No fue requerida aprobación por comité de ética. Resultados: La mayor TEH se registró en 2023, con 64,15/100.000 habitantes. El grupo etario con mayor TEH se encontró entre 20 a 44 años, alcanzando 82,90/100.000 egresos. La forma clínica más frecuente fue la endometriosis del útero, representando el 50,55% del total de casos. Discusión: El aumento de la TEH en 2023 podría asociarse a una mayor cantidad de intervenciones asociadas a esta patología. La mayor TEH en mujeres de 20 a 44 años, coincide con lo descrito en la literatura y podría vincularse al estrés oxidativo generado por la menstruación. La alta frecuencia de endometriosis uterina podría deberse mayor accesibilidad diagnóstica, mientras que otras localizaciones y la endometriosis no especificada generan más dificultades para realizar un diagnóstico certero. Conclusión: Existen grupos de riesgo definidos asociado a esta patología. Se recomienda la realización de nuevas investigaciones dado que afecta la salud pública chilena desde el punto de vista laboral, asistencial, reproductivo y psicológico. Summary Introduction: Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterine cavity. Objective: To describe the Hospital Discharge Rate (HDR) of endometriosis during the period 2020 to 2023 in Chile. Materials and Methods: An observational, descriptive, and quantitative study was conducted using data from the Department of Health Statistics and Information (DEIS) and the National Institute of Statistics (INE). Descriptive analysis was performed using central tendency measures, with graphs and tables created in Excel. Ethical approval was not required. Results: The highest HDR was recorded in 2023, with a value of 64.15/100,000 inhabitants. Aged between 20–44 years had the highest HDR with a value of 82.90/100,000 discharges. Uterine endometriosis had the highest number of cases, accounting for 50.55%. Discussion: The increase in HDR in 2023 may be associated with a higher number of interventions related to this condition. The higher HDR among women aged 20 to 44 is consistent with the literature and may be linked to oxidative stress caused by menstruation. The high frequency of uterine endometriosis could be due to greater diagnostic accessibility, unlike other locations and unspecified endometriosis pose challenges for accurate diagnosis. Conclusion: It can be concluded that there are risk groups associated with this pathology. We recommend further research, as endometriosis affects public health in Chile from occupational, healthcare, reproductive, and psychological perspectives.
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Introduction

Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterine cavity.

Objective

To describe the Hospital Discharge Rate (HDR) of endometriosis during the period 2020 to 2023 in Chile.

Materials and methods

An observational, descriptive, and quantitative study was conducted using data from the Department of Health Statistics and Information (DEIS) and the National Institute of Statistics (INE). Descriptive analysis was performed using central tendency measures, with graphs and tables created in Excel. Ethical approval was not required.

Results

The highest HDR was recorded in 2023, with a value of 64.15/100,000 inhabitants. Aged between 20–44 years had the highest HDR with a value of 82.90/100,000 discharges. Uterine endometriosis had the highest number of cases, accounting for 50.55%.

Discussion

The increase in HDR in 2023 may be associated with a higher number of interventions related to this condition. The higher HDR among women aged 20 to 44 is consistent with the literature and may be linked to oxidative stress caused by menstruation. The high frequency of uterine endometriosis could be due to greater diagnostic accessibility, unlike other locations and unspecified endometriosis pose challenges for accurate diagnosis.

Conclusion

It can be concluded that there are risk groups associated with this pathology. We recommend further research, as endometriosis affects public health in Chile from occupational, healthcare, reproductive, and psychological perspectives. Referencias 1. Taylor H, Kotlyar A, Flores V. Endometriosis is a chronic systemic disease: clinical challenges and novel innovations. Lancet. 2021; 397: 839-852. 2. Zondervan K, Becker M, Missmer S. Endometriosis. N ENG J MED. 2020; 382: 1244-1256. 3. Organización Mundial de la Salud. Endometriosis [Internet]. 2023. (consultado 30 de enero de 2025). Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/endometriosis 4. Scarella-Chamy A, Miranda-Mendoza I. Evaluación clínica y manejo de la endometriosis: resumen de la Orientación Técnica MINSAL para el manejo de personas con endometriosis. Rev Chil Obstet Ginecol. 2023; 88(2): 126-136. 5. Smolarz B, Szyllo K, Romanowicz H. Endometriosis: Epidemiology, Classification, Pathogenesis, Treatment and Genetics (Review of Literature). Int J Mol Sci. 2021; 22: 10554. 6. Paing A, Elliff-O'Shea L, Boardman L, Turner D, Glennie L; Guideline Committee. Diagnosis and management of endometriosis: summary of updated NICE guidance. BMJ. 2024 Nov 27;387:q2452. doi: 10.1136/bmj.q2452. 7. Poveda C, Oñate Tapia D, Álvarez E, León V, Sandoval V, Mena González B. Tasa de egresos hospitalarios por enfermedad inflamatoria pélvica femenina en mujeres desde los 10 años de edad durante el período 2020 a 2023 en Chile. Austral J Biohealth. 2025;2. Disponible en: https://australjournalofbiohealth.org/index.php/umag/article/view/11 8. Céspedes P, Correa E. Reproducción asistida en Chile: una mirada global para el desafío de ofrecer un acceso oportuno. Rev médica Clín Las Condes [Internet]. 2021;32(2):189–95. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0716864021000237 9. Weissman A, Hart R, Greenblatt EM, et al. Burden of endometriosis: infertility, comorbidities, and healthcare resource utilization. J Clin Med. 2022;11(5):1340. doi:10.3390/jcm11051340. 10. Programa Nacional de Salud de la Mujer, Departamento de Ciclo Vital, División de Prevención y Control de Enfermedades. Orientaciones técnicas para la atención integral de la endometriosis. Santiago: Ministerio de Salud; 2023. Disponible en: https://diprece.minsal.cl/wp-content/uploads/2023/10/ORIENTACIONES-TECNICAS-PARA-LA-ATENCIONINTEGRAL-DE-LA-ENDOMETRIOSIS-Resolucion-exenta-N%C2%B02923.pdf 11. Le Moal J, Goria S, Chesneau J, Fauconnier A, Kvaskoff M, De Crouy-Chanel P, Kahn V, Daraï E, Canis M. Increasing incidence and spatial hotspots of hospitalized endometriosis in France from 2011 to 2017. Sci Rep. 2022 Apr 28;12(1):6966. doi: 10.1038/s41598-022-11017-x. PMID: 35484205; PMCID: PMC9050825. 12. Estes SJ, Soliman AM, Epstein AJ, Bond JC, Gordon K, Missmer SA. National trends in inpatient endometriosis admissions: Patients, procedures and outcomes, 2006-2015. PLoS One. 2019 Sep 19;14(9):e0222889. doi: 10.1371/journal.pone.0222889. PMID: 31536593; PMCID: PMC6752838. 13. Maraschini A, Ceccarelli E, Giangreco M, Monasta L, Manno V, Catelan D, Stoppa G, Biggeri A, Ricci G, Buonomo F, et al. Development of an Italian National Epidemiological Register on Endometriosis Based on Administrative Data. J Clin Med. 2024;13(11):3087. doi: 10.3390/jcm13113087. 14. Amro B, Ramirez Aristondo ME, Alsuwaidi S, Almaamari B, Hakim Z, Tahlak M, Wattiez A, Koninckx PR. New understanding of diagnosis, treatment and prevention of endometriosis. Int J Environ Res Public Health. 2022 May 31;19(11):6725. doi: 10.3390/ijerph19116725. PMID: 35682310; PMCID: PMC9180566. 15. Rocha ALL, Reis FM, Petraglia F. Hormone Therapy and Risk of Endometriosis Recurrence after Menopause: A Systematic Review. Cancers (Basel). 2024;16(4):809. Disponible en: https://www.mdpi.com/2072-6694/16/4/809 Esta obra está bajo una licencia internacional Creative Commons Atribución-CompartirIgual 4.0. Derechos de autor 2025 Camila Gomez

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