Endometriosis as a Differential Diagnosis in a 17-Year-Old Patient with Low Back and Radicular Pain: A Case Report

Mercedes Vergara, Miryam Vergara, Daniele Ceron, Gloria Giglioni, Gabriella Di Crescenzo, Elisa Burani
In: Women · 2025 · vol. 5(3) , pp. 28 · doi:10.3390/women5030028 · W4412895410
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This case report details a 17-year-old presenting with low back and radicular pain, ultimately diagnosed with endometriosis after standard treatments failed, emphasizing its consideration in younger patients.

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Abstract

Endometriosis is a benign and often underdiagnosed condition that affects women of reproductive age, typically between 18 and 45 years. It can cause infertility and pain, including radicular pain and low back pain (LBP). The aim of this case report is to emphasize the importance of making a differential diagnosis when facing LBP and radicular symptoms. We report the case of a 17-year-old female patient, R.A., presented with a significant LBP (NPRS 8/10) radiating from her lumbar spine to her right buttock and occasionally to both legs, accompanied by weakness. She revealed exacerbation of pain during menstruation, despite being under hormonal contraceptive treatment. After three physiotherapy sessions that included education, manual therapy and exercise, the patient’s pain persisted so her physiotherapist recommended an evaluation in the emergency department, where standard radiography did not reveal any significant findings. Physiotherapy continued until the fifth session, when the patient agreed to undergo evaluation at a specialized endometriosis centre. Further investigations revealed endometriotic tissue on the uterosacral ligament, leading to hormonal therapy adjustment, with which pain gradually decreased to a manageable level (NPRS 2/10). This case report highlights the importance of an early differential diagnosis in patients with LBP, as endometriosis can present not only in older women but also in younger patients, including those already on oral contraceptives. Therefore, to mitigate the risk of pattern recognition bias, clinicians must maintain a high index of suspicion for endometriosis, even in atypical or unlikely clinical presentations.

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endometriosisinfertility

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