The correlation between the cerebroplacental ratio and fetal arterial blood gas in appropriate-for-gestational-age fetuses: A cross-sectional study.

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This cross-sectional study of 347 appropriate-for-gestational-age fetuses found that a third-trimester cerebroplacental ratio below 0.67 multiples of the median was associated with higher rates of fetal distress, emergency cesarean section, and neonatal intensive care unit admission.

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This cross-sectional study evaluated the correlation between the cerebroplacental ratio (CPR) and fetal arterial blood gas parameters in 403 appropriate-for-gestational-age fetuses at term. Researchers measured CPR via Doppler ultrasound before delivery and compared neonatal outcomes, including umbilical artery pH, Apgar scores, and rates of emergency cesarean section or NICU admission, between groups with high and low CPR values. The findings indicated that a low CPR was significantly associated with lower neonatal pH, increased risk of intrapartum fetal distress, and higher likelihood of adverse perinatal outcomes such as emergency surgery and intensive care admission. Relevance to endometriosis: The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

BackgroundThe cerebroplacental ratio (CPR) is an important index for predicting adverse pregnancy outcomes in small-for-gestational-age and appropriate-for-gestational-age fetuses.ObjectiveTo find out whether there is an association between the CPR level and the blood cord gases analysis in appropriate for gestational age fetuses.Materials and methodsThis cross-sectional study included 347 pregnant women at the gestational age of 37-40 wk. Patients had an appropriate-for-gestational-age fetus confirmed from their first ultrasonography results. Participants were divided into two groups based on their CPR, measured before delivery. Finally, after delivery, arterial blood gas level and the incidence of emergency cesarean section, intrapartum fetal distress and neonatal intensive care unit admissions were compared between the two groups.ResultsFifty-four (15.6%) cases had a CPR below the detection limit of the assay. The incidence of fetal distress, emergency cesarean section, neonatal hospitalization in the neonatal intensive care unit, and pH < 7.2 were significantly lower in women with CPR ≥ 0.67 multiples than in women with a CPR < 0.67 multiples of the median.ConclusionThe third-trimester CPR is an independent predictor of stillbirth and perinatal mortality and morbidity. The role of UA/MCA Doppler and the CPR in assessing the risk of adverse pregnancy outcomes should be evaluated prospectively.
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Section

The CPR is an important factor in predicting the morbidity and mortality of infants. And a low CPR, even in normal weight fetuses, can be a sign of hypoxemia and placental insufficiency. However, this claim needs further investigation.

Coi Statement

The authors declare that there is no conflict of interest.

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last seen: 2026-09-06T09:34:12.023084+00:00
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