Novel [corrected] medical management of primary bladder endometriosis with dienogest: a case report

Hiroshi Takagi, H Takagi, Takagi H, K. Matsunami, Matsunami K, Ichigo S, S Ichigo, Satoshi Ichigo, Imai A, Atsushi Imai, A Imai
Clinical and experimental obstetrics & gynecology · 2011 · vol. 38(2) , pp. 184–5 · PMID:21793288 · W127873466
Case report OA: closed CC0 ⤵ 12 in-corpus citations
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This case report details the successful medical management of primary bladder endometriosis using six months of oral dienogest, leading to lesion reduction and symptom relief in a 39-year-old woman.

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Abstract

BACKGROUND: Because of its low incidence, medical treatment of has not yet been well established although surgical excision is generally considered effective. We report the first case of primary bladder endometriosis successfully managed with a novel progestin dienogest. CASE: A 39-year-old woman, nulligravida, presented with lower urinary tract symptoms, especially during menstruation. Cystoscopy, with subsequent cold cup biopsy, revealed a solitary submucosal mass (2 x 2 cm) in the bladder on the posterior wall; histopathology revealed the diagnosis of extraperitoneal endometriosis. MRI and laparoscopy confirmed no peritoneal endometriosis implants or adenomyosis. She was treated with oral 2 mg/day dienogest for six months. The measurable lesion exhibited a remarkable reduction in its size, accompanied with immediate relief of the lesion-related symptoms. At one year after medication cessation, she is well and symptom-free. CONCLUSION: Dienogest may be a novel conservative alternative for bladder endometriosis, in particular for women who wish to avoid surgical intervention.

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Condition tags

endometriosisadenomyosisbladder_endometriosis

MeSH descriptors

Endometriosis Hormone Antagonists Nandrolone Urinary Bladder Diseases Adult Adult Endometriosis Endometriosis Female Female Hormone Antagonists Hormone Antagonists Humans Humans Nandrolone Nandrolone Nandrolone Pregnancy Pregnancy Urinary Bladder

Citation neighborhood (2-hop)

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]

Cited by (12)

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License: CC0 · commercial use OK