Dysmenorrhea, endometriosis, adenomyosis: clinical and pathogenetic relationships

А. Л. Унанян, Sidorova Is, А Д Никонец, Yu V Kostina, N N Kuzenkova, A M Elisavetskaia, D.V. Baburin
In: Gynecology · 2018 · vol. 20(1) , pp. 9–15 · doi:10.26442/2079-5696_20.1.9-15 · W2895810870
article OA: gold CC0 ⤵ 3 in-corpus citations
🔓 Open OA copy View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This review examines the prevalence, clinical relevance, and pathogenetic links between dysmenorrhea and gynecological conditions like endometriosis and adenomyosis.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 ⓘ

This review discusses dysmenorrhea in women of reproductive age, distinguishing primary from secondary dysmenorrhea and summarizing epidemiology, risk factors, pain phenotypes, and proposed mechanisms, including increased prostaglandin synthesis, uterine hypercontractility, and impaired uterine blood flow. It reports that primary dysmenorrhea is often underrecognized, highlights associations with altered pain sensitivity and central nervous system changes, and notes that parity, oral contraceptives, and other factors are linked in the literature to risk reductions or symptom changes; a key caveat is that many comparisons are based on heterogeneous studies with varying diagnostic criteria, and the paper itself emphasizes that causal direction between pain sensitivity and dysmenorrhea remains unclear. It also summarizes evidence on symptom impact (quality of life, psychological distress, central sensitization) and reviews therapeutic evidence where data for some modalities are limited or uncertain. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

This publication is devoted to the most common problem in women of reproductive age - dysmenorrhea. Unfortunately, the underestimation of the importance of dysmenorrhea often occurs on the part of both patients and doctors. Meanwhile, dysmenorrhea causes not only a decrease in the quality of life, but also a number of serious disorders, including the risk of developing endometriosis, adenomyosis and even tumorous diseases. With such articles as prevention and prevention of diseases.

My notes (saved in your browser only)

Condition tags

endometriosisadenomyosisdysmenorrhea

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (86)

Cited by (3)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK