Endometriosis Is Associated With Higher Healthcare Utilization and Upper Gastrointestinal Symptoms
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This study found that endometriosis is linked to increased healthcare use and a higher incidence of upper gastrointestinal symptoms like nausea and vomiting.
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Abstract
Endometriosis is a chronic inflammatory disease affecting 10%-15% of women, with symptoms including abdominopelvic pain, dysmenorrhea, and menorrhagia. Up to 90% experience gastrointestinal (GI) symptoms including constipation, bloating, and nausea/vomiting.1 Females with endometriosis are at 3-5 times greater risk of developing IBS than healthy women,2,3 with rates of IBS as high as 52%.4 Another study demonstrated 37% of those with IBS also had endometriosis, much higher than the typical prevalence of endometriosis.5 Patients with IBS and endometriosis experience lower pain thresholds and more painful menstrual cycles than those with either condition alone. This amplification of pain experiences can increase health care utilization and decrease quality of life.
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References (7)
- Bowel Endometriosis Mimicking Crohn Disease via openalex
- Endometriosis and inflammatory bowel disease: A systematic review of the literature via openalex
- Endometriosis and irritable bowel syndrome: a systematic review and meta-analysis via openalex
- Endometriosis in patients with irritable bowel syndrome: Specific symptomatic and demographic profile, and response to the low FODMAP diet via openalex
- Relevance of gastrointestinal symptoms in endometriosis via openalex
- Visceral hypersensitivity in endometriosis: a new target for treatment? via openalex
- W3012416857 via openalex
Cited by (8)
- Dietary and Environmental Exposure to Toxic Elements in Endometriosis: A Missing Piece of the Etiological Puzzle? 2026
- ATP–P2X3 Signaling as a Shared Neural Sensitization Pathway in Endometriosis and Irritable Bowel Syndrome: Mechanisms and Therapeutic Implications 2026
- Gastrointestinal tract endometriosis: Clinicopathologic features and anatomic distribution in an institutional cohort 2026
- Antagonizing the corticotropin-releasing hormone receptor 1 with an orally bioavailable drug reduces endometriosis pain and associated adhesions† 2026
- Characteristics of endometriosis patients referred for tilt table testing 2026
- Gut feeling: understanding the endometriosis-digestive link to enhance patient care and symptom control 2025
- The Importance of Diet in the Treatment of Endometriosis 2024
- The Importance of Diet in the Treatment of Endometriosis 2024
Source provenance
- europepmc
- last seen: 2026-09-08T06:17:11.951632+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-09-08T06:14:45.040243+00:00
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