Soluble CD44 concentration in the serum and peritoneal fluid samples of patients with different stages of endometriosis

Farhad Mashayekhi, Hadis Aryaee, Ebrahim Mirzajani, Ashraf Ale Yasin, Abdolsatar Fathi
Archives of gynecology and obstetrics · 2015 · vol. 292(3) , pp. 641–645 · doi:10.1007/s00404-015-3654-9 · PMID:25711649 · W2083459270
article OA: closed CC0 ⤵ 4 in-corpus citations
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⚙ AI-generated summary by claude@2026-06+body, 2026-06-08 ⓘ

This study measured soluble CD44 in serum and peritoneal fluid from endometriosis patients, finding increased levels in all stages compared to controls, with higher concentrations correlating with advanced disease.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This study measured soluble CD44 (sCD44) levels in serum and peritoneal fluid (PF) from 39 control samples (normal healthy) and 130 endometriosis patients across stages I–IV, alongside total protein concentration and a reported cMet ELISA component. Across all examined specimens, sCD44 was detectable, and from stage I through stage IV endometriosis the sCD44 levels in serum and PF were significantly higher than in controls, with advanced stages showing greater expression. The paper specifically notes categorization by stage and does not report a detailed limitation such as sample matching or statistical caveats in the abstract. This paper is centrally about endometriosis — it assesses how serum and peritoneal fluid soluble CD44 varies with endometriosis stage.

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Condition tags

mesh:D004715endometriosis

MeSH descriptors

Ascitic Fluid Endometriosis Endometrium Hyaluronan Receptors Hyaluronan Receptors Adult Ascitic Fluid Case-Control Studies Endometriosis Endometriosis Endometrium Endometrium Enzyme-Linked Immunosorbent Assay Female Humans Hyaluronan Receptors Middle Aged Peritoneum Peritoneum Severity of Illness Index

Citation neighborhood

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References (21)

Cited by (4)

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