Genetics of endometriosis
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⤵ 5 in-corpus citations
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This paper discusses the genetic basis of endometriosis as a multifactorial polygenic disorder and the ongoing efforts to identify susceptibility genes using advanced molecular techniques.
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Abstract
UNLABELLED: Endometriosis is a multifactorial disease that can affect up to 10-15% of women in their reproductive age. Epidemiological studies indicate that it is a polygenic disorder with recurrence risks in first-degree relatives of about 5-7%. Thus, the present aim of different research groups is to identify genetic variations in obvious candidate gene that could be associated with an increased susceptibility to endometriosis. The great advancement in molecular biology techniques make this task certainly possible, although particular attention needs to be paid to the study design in order to achieve reliable
RESULTS: The data obtained by such studies will allow to expand our knowledge on the pathogenesis of the disease and, more importantly, to develop individualized therapies and prevention strategies to apply at high-risk populations.
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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. Outer rings show 2-hop neighbours — papers reached through the immediate citers/citees. [ collapse to 1-hop ]
Cited by (5)
- A current view of the role of epigenetic changes in the aetiopathogenesis of endometriosis 2015
- Understanding the pathogenesis of endometriosis through proteomics: recent advances and future prospects 2013
- Regulación del crecimiento del tejido endometrial en respuesta a nuevas alternativas terapéuticas propuestas para tratar la endometriosis 2012
- Investigating endometriosis: symptoms, diagnosis and treatment 2006
- Efectos del tratamiento quirúrgico de la endometriosis ovárica sobre los resultados reproductivos en pacientes que realizan tratamientos de fecun- dación "In Vitro" Effects of the surgical treatment of the ovarian endometriosis on the reproduc- tive results in patients that carry out treatment of "In Vitro" fertilization 2006
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- europepmc
- last seen: 2026-10-09T06:09:53.026058+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-10-08T21:03:24.829172+00:00
License: CC0
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