General pharmacology

Gen Pharmacol · ISSN (print) 0306-3623 · 3 papers in corpus
other 1995
Danazol decreases transcription of estrogen receptor gene in human monocytes
doi:10.1016/0306-3623(94)00227-e ·PMID:7540578

1. Administration of danazol for over one month reduced the levels of estrogen receptor (ER) and its mRNA to approximately 50 and 20%, respectively in monocytes. 2. Danazol did not alter the degradation rate of ER mRNA in monocytes. 3. Dana…

lab-animal 1992
Estrogen binding sites in peripheral blood monocytes and effects of danazol on their sites in vitro
doi:10.1016/0306-3623(92)90150-i ·PMID:1397976

1. This study was designed to investigate the presence of estrogen type I (high affinity, low capacity) and type II (low affinity, high capacity) binding sites in human peripheral blood monocytes and the effects of danazol on these sites. 2…

lab-animal 1991
Rationale for frequency and dose of administration in gestrinone therapy for pelvic endometriosis in the experimental model of rabbit uterus
doi:10.1016/0306-3623(91)90014-w ·PMID:1869024

1. Gestrinone has been used for treatment of pelvic endometriosis, in doses of 2.5 mg twice a week. This study is designed to clarify it from the dynamics of sex steroid receptors in rabbit uterus. 2. Four different regimens were scheduled,…