Obstetrics and gynecology

Clinicopathologic data are presented for 22 cases of malignant mixed mesodermal tumors of the ovary of both homologous and heterologous types. The results substantiate previous reports of low parity in the almost exclusively postmenopausal …

Multifocal disease, both benign and malignant, is seen commonly in the lower genital canal. Conversely, malignancies developing concomitantly in the uterus and ovary are frequently diagnosed as metastatic disease. In this series of 54 cases…

Twenty patients with moderate to very severe painful menstrual periods secondary to endometriosis were treated in a double-blind, four-period, crossover clinical trial with naproxen sodium and placebo. Complete or substantial pain relief wa…

Excised tubal segments from 42 women with uterotubal junction obstruction were studied histologically to evaluate the pathologic spectrum of disease and correlate this with clinical data. The most frequent lesion encountered was obliterativ…

A case of supernumerary ovary is presented. This rare gynecologic abnormality, which is usually diagnosed on laparotomy or autopsy, was noted on laparoscopy.

To assess the presence of autoimmune factors in patients with endometriosis, endometrial homogenates, peritoneal fluid, and serum were evaluated in 23 patients with endometriosis and 22 control subjects. The methods used were Ouchterlony im…

The coexistence of ovarian neoplasms and adenocarcinoma of the cervix occurs more often than generally realized. Of 390 women with adenocarcinoma of the cervix, the ovaries were available for histologic review in 161. Neoplasms were present…

Endometriosis associated with massive ascites is an unusual combination unknown to most practicing gynecologists. Only 11 cases have been reported since this entity was first described by Brews in 1954. The authors report an additional case…

Laparoscopy was used to evaluate 100 women who consistently reported pelvic pain in the same location for a minimum of six months. These findings were compared with those of 50 asymptomatic women who underwent laparoscopy for tubal ligation…

Recent investigations suggested a possible immunologic etiology for endometriosis. To determine whether cellular immunity may be affected in patients with endometriosis, peripheral lymphocyte populations were investigated in 31 confirmed en…

A well-documented case of extraovarian endometriosis undergoing malignant transformation is presented. A vaginal focus of endometriosis was biopsied over a 13-year interval during which time progression from benign to malignant disease was …

Laparoscopic surgery, the accepted procedure for several indications, still has some limitations, mainly due to the risk of uncontrollable bleeding and damage to the surrounding tissues that may result from the procedure. With the advent of…

To elucidate the roles of prostaglandins in peritoneal fluid and sex steroids in patients with endometriosis (N = 29), tubal disorders (N = 15), and unexplained infertility (N = 13), assays were performed using 6-keto-prostaglandin F1 alpha…

Endometriosis of the ureter is rare. The authors describe a case of ureteral endometriosis presumed on clinical and radiologic grounds to be a primary ureteral malignancy. The unique feature of the present case is the development, after lon…

Blood was found in the peritoneal fluid in 90% of women with patent tubes at laparoscopy during perimenstrual time. If the fallopian tubes were occluded, then only 15% of patients had evidence of blood in the pelvis. Also, 90% of patients w…

To address the question of when to perform an appendectomy in the surgical treatment of endometriosis, a series of 500 consecutive appendectomies was reviewed. In 104 patients with pelvic endometriosis who were undergoing appendectomy, the …

The hormonal effects of danazol and of a long-acting gonadotropin-releasing hormone analogue (GnRH-a) were studied in women with endometriosis and those with oophorectomy. During danazol treatment, total serum concentrations of estrone and …

It is generally accepted that laparoscopy should be performed if a woman's basic infertility evaluation reveals no abnormalities. Although it has been shown that a significant number of these patients have unsuspected pelvic pathology that …

Cul-de-sac fluid collected at laparoscopy from 58 women during various stages of the menstrual cycle was evaluated by volume and by estradiol and progesterone content. Volumes were consistently higher in the third cycle week, especially wit…

Photocoagulation of peritoneal implants of endometriosis was performed in five women during laparoscopy to evaluate infertility. A 600-microns flexible quartz fiber was passed into the abdomen through a suprapubic incision using an instrume…

Pregnancy complicated by ovarian endometrioma is rare; only four cases have been reported. Although infertility and endometriosis are closely related, endometriosis may be found with pregnancy and, although it has been written that endometr…

Sampson's concept of endosalpingiosis is reexamined in light of histologic findings in the fallopian tubes of 54 women who underwent elective sterilization and subsequent hysterectomy and bilateral salpingo-oophorectomy. It was not possible…

Pregnancy success was evaluated in 48 women following surgical correction of a vaginal obstruction due to imperforate hymen (N = 22) or to a complete transverse vaginal septum (N = 26). Pregnancy success was more likely to occur following s…

This case study of a sclerosing stromal tumor of the ovary in a 29-year-old woman demonstrates that the tumor was a functioning lesion that secreted estradiol, progesterone, and testosterone. Clinically, there was anovulation with resultant…