Gynecologic oncology reports

Primary peritoneal malignant tumors are exceptional. Among them, clear cell carcinoma is extremely rare, being only thirteen cases previously reported in the literature since 1990. We report a case of a 48-year-old Caucasian woman who was t…

•Primary signet ring cell carcinoma in ovarian mucinous tumor is rare.•The most important differential diagnosis is metastatic carcinoma.•We report a case of primary ovarian signet ring cell carcinoma in mucinous tumor.•Clinicopathological …

•A woman with a history of Stage IA low-risk uterine adenosarcoma presented with shortness of breath and rib pain.•She was found to have recurrent metastatic disease with resultant fatal SVC Syndrome.•Better methods to determine which patie…

Cancer antigen 125 (CA 125) is a transmembrane glycoprotein expressed on the surface of germinal epithelium and other tissues derived from embryonic coelomic epithelium (Bischof, 1993). CA 125 is a useful biomarker to detect treatment respo…

•Cervical cancer occurring in patients with OHVIRA syndrome is very rare.•This case reports on HPV-negative adenocarcinoma located in the nonvisible cervix.•Colposcopy and imaging are essential for cervical cancer with uterine malformation.…

•Bartholin's gland carcinoma, adenoid cystic subtype, can occur in younger patients.•These cancers are at high risk of local recurrence and surveillance is needed.•There remains limited evidence specific to these cancers.

Ovarian endometrioid adenocarcinoma with yolk sac component has been reported in fewer than twenty cases in the literature. A majority of the diagnoses are described in postmenopausal women without specific reference to germline genetic tes…

•A cul-de-sac endometrioid carcinoma adjacent to extraovarian endometriosis was identified during remission of endometrial cancer.•The origin of the cul-de-sac tumor was malignant transformation of deep infiltrating endometriosis.•Endometri…

The objectives of this study were to determine both surgical and subsequent cancer outcomes for high-risk women from the University of Virginia's High-Risk Breast/Ovarian Cancer clinic undergoing ovarian cancer risk-reducing surgery. Retros…

•Ectopic choriocarcinoma coexistent with viable IUP is rare but has been reported.•Atypical and proliferative trophoblasts are normal in an early conceptus.•Evaluation including MRI and CXR did not reveal metastatic choriocarcinoma.•IHC ana…

•Breast cancer originating from the vulva is extremely rare.•There are no guidelines for the treatment of such cancers.•More research is needed to uncover a possible genetic predisposition.

Primary vaginal leiomyosarcoma (LMS) is a rare entity with limited data on optimal treatment approach. Most previously reported cases utilize an open or transvaginal surgical approach for primary tumor resection. Minimally invasive surgery …

We describe a case of the first successful treatment of platinum refractory clear cell ovarian cancer with secondary cytoreductive surgery and placement of Calypso transponders to facilitate post-operative volumetric arc radiation therapy. …

•Extragonadal malignant transformation of endometriosis can occur after oophorectomy.•Endometriosis-associated malignancy can occur in the absence of hormone replacement.•Estrogen and progesterone receptor status can influence treatment str…

Data from colon, breast and prostate cancers suggest that aspirin users have reduced mortality. While the direct mechanism remains uncertain, aspirin can suppress the COX-dependent and independent pathways involved in tumor progression. We …

BACKGROUND: Various ovarian neoplasms may show histological findings that are morphologically indistinguishable from adult granulosa cell tumor (AGCT). CASE PRESENTATION: A 36 year-old women presented with left lower extremity pain and num…

•A histologically low-grade cervical clear cell lesion was observed.•Proliferating cells were seen only at the periphery of this lesion.•Due to its low proliferation index, this may represent a precursor of clear cell carcinoma.•Further def…

Endometriosis is a condition wherein an ectopic layer of endometrial tissue arises in an extra-uterine location, often effecting significant pelvic pain and infertility. While very uncommon, there have been reported cases of endometriosis u…

BACKGROUND: Sex cord tumors with annular tubules (SCTAT) are a rare (2%) subtype of ovarian sex cord-stromal tumor. SCTATs are usually cured at time of diagnosis by surgical resection with an oophorectomy. SCTATs have a 100%(disease related…

•While endosalpingiosis is often asymptomatic & incidental, florid cystic endosalpingiosis can have a variable presentation•Cystic endosalpingiosis can be difficult to differentiate from other non-neoplastic peritoneal inclusion cysts•Altho…

•A woman with recurrent ovarian cancer presented with rectal bleeding and cramping abdominal pain.•CT showed ileocolic intussusception.•In ovarian cancer, intussusception requires surgery whereas other bowel obstructions are initially treat…

This study evaluates a novel technique of laparoscopic ovarian transposition performed by Gynecologic Oncologists prior to pelvic radiation for gynecologic cancer. A retrospective review was completed of all patients that underwent laparosc…

A solitary pelvic tumor after treating a primary endometriosis-related neoplasm is usually considered a recurrence but may actually be a primary endometriosis-related peritoneal neoplasm. A Japanese woman in her late 60s was referred to our…

•Mullerian Carcinosarcoma (MC) is one of the rarest endometriosis associated malignancies (EAM).•Atypical endometriosis can undergo variety of metaplastic changes causing diagnostic dilemma.•Atypical endometriosis possibly represents a prec…