Journal of Human Reproductive Sciences

BACKGROUND: Oocyte retrieval requires effective sedation that ensures patient comfort without compromising reproductive outcomes. Although multiple sedative agents are routinely employed during oocyte retrieval, the optimal sedative regimen…

BACKGROUND: Polycystic ovary syndrome (PCOS) is a leading cause of anovulatory infertility. Letrozole is the first-line agent for ovulation induction; however, response to the standard 5-day regimen may be suboptimal in some women. AIM: Th…

Scientific writing is an essential skill for clinicians and researchers to disseminate their research findings effectively. This narrative review discusses key aspects, including the formulation of an appropriate research question, the sele…

BACKGROUND: Low-dose aspirin (LDA) has been used during assisted reproduction; however, the evidence supporting its use remains conflicting. AIM: To assess whether LDA improves the clinical pregnancy rate (CPR) in a patient's first autolog…

Deep infiltrating endometriosis (DIE) is a severe pathology requiring complex pelvic surgery, which carries a rare but serious risk of uterine rupture during pregnancy. We report a primiparous patient who achieved pregnancy through in vitro…

BACKGROUND: Recurrent implantation failure (RIF) remains a major challenge in assisted reproductive technology. Acupuncture has been used as a complementary therapy to improve pregnancy outcomes, but its efficacy in women with RIF remains u…

BACKGROUND: Embryo selection in IVF often relies on inner cell mass (ICM) morphology as a predictor of implantation. However, in static two-dimensional images, ICM visibility may be limited by technical factors like orientation or focus, ra…

BACKGROUND: Studies have assessed the impact of culturing warmed cleavage-stage embryos to blastocyst in frozen embryo transfer (FET) cycles; there is a paucity of studies that have evaluated the impact of warming of day 3 embryos and cultu…

Intramyometrial pregnancy is a rare type of ectopic pregnancy that is difficult to diagnose. We report a case of intramyometrial pregnancy with uterine rupture following frozen embryo transfer (FET), highlighting both the diagnostic challen…

BACKGROUND: Genetic polymorphisms in the luteinizing hormone (LH) β-subunit gene have been associated with responses to controlled ovarian hyperstimulation (COH) in in vitro fertilisation (IVF) patients. Variants in rs1800447 and rs34349826…

Adenomyosis is a complex, heterogeneous condition characterised by the development of ectopic endometrial glandular and stromal tissue within the myometrium. Surrounding it, there is reactionary fibrosis, hyperplasia and hypertrophy of the …

The zona pellucida (ZP) is essential in reproductive biology, covering sperm selection, species-specific fertilisation, inhibition of polyspermy and stability of blastomeres in embryos. This case report highlights the developmental potentia…

BACKGROUND: Fibroblast growth factors (FGFs) play a key role in embryo implantation and support endometrial trophoblastic interaction. AIM: The aim of the study was to evaluate the association between FGF-1 (rs34011) gene variety and its s…

AIM: The objective of this document is to provide guidance to the infertility specialist, gynecologist, embryologist, and counselors on the management of sub-fertility and brief them with the recent advances in the field. These recommendati…

BACKGROUND: As the male factor in infertility is on rising trend, we need a promising tool for sperm selection to improve the embryo development. AIM: The present study compares the embryological and clinical parameters between physiologic…

BACKGROUND: Polycystic ovary syndrome (PCOS), a common endocrine disorder, is linked to increased risks of endometrial cancer (EC) and ovarian cancer (OC). Our study utilises bioinformatics analysis to identify shared gene signatures and el…

BACKGROUND: Polycystic ovarian syndrome (PCOS) is one of the common causes of anovulatory infertility among women in the reproductive age group. Women with PCOS and obesity often have difficulty in conceiving, and they are more prone for de…

Herlyn-Werner-Wunderlich syndrome in females, also known as obstructed haemivagina and ipsilateral renal agenesis (OHVIRA), and Zinner's syndrome, also known as OSVIRA in males, are two rare congenital syndromes affecting the urogenital tra…

BACKGROUND: An increasing number of studies have demonstrated that excessive proliferation and apoptosis play a pivotal role in the development of endometriosis. AIM: The aim of the study was to evaluate the expression of long non-coding R…

Uncommon presentations of granulomatous salpingitis are pseudoxanthoma salpingitis (PSX) and xanthogranulomatous salpingitis (XGS). The clinical features and image modalities can mimic ovarian malignancy. Thus, a proper pre-operative evalua…