Editorial Commentary.

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This editorial introduces the July–September 2025 issue, highlighting research on IVF protocols, male infertility, and adenomyosis-associated intramyometrial pregnancy.

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This editorial commentary introduces the July–September 2025 issue of the Journal of Human Reproductive Sciences, highlighting its first impact factor and thanking previous and current editorial teams. It summarizes five original articles and case reports covering topics such as IVF stimulation protocols, embryo warming logistics, vitamin D effects on sperm, genetic polymorphisms in infertility, and oocyte cryopreservation challenges. The text specifically notes a case report describing an intramyometrial pregnancy occurring in a woman with diffuse adenomyosis following frozen embryo transfer. Relevance to endometriosis: adenomyosis is explicitly mentioned in the context of a rare pregnancy complication reported within this issue.

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The editorial team welcomes you to the July–September 2025 issue of the Journal of Human Reproductive Sciences. We are excited to share our first impact factor of 1.1, as released by Clarivate Analytics in the 2025 version of the Journal Citation Reports. We would like to thank our past Editor-in-Chief, Dr. Kamini Rao, Dr. Madhuri Patil and Dr. Padma Rekha Jirge, as well as the previous editorial team and reviewers, for their valuable contributions and support for our journal. I would also like to thank the current editorial team members, authors and our readers for their support, which has helped us grow year on year. For the new issue, we have five original articles, one case series and two case reports. In a retrospective study by Kothekar et al., the authors compared the efficacy of progesterone primed ovarian stimulation versus GnRH antagonist in In vitro fertilization (IVF) and reported similar outcomes. In another retrospective study by Singh et al., the authors reported similar frozen embryo treatment outcomes following the previous day versus the same day warming of day 3 cleavage stage embryo, suggesting that a flexible approach can be taken based on logistics and workflow without compromising the results. In a study by Hilali et al., the authors reported a beneficial impact of adding Vitamin D on sperm parameters and suggested a potential therapeutic option for male infertility. In an association study, the authors reported the association of GnRH1 polymorphism rs6185 in women with polycystic ovarian syndrome. In another study, the authors explored the association of angiotensin-converting enzyme insertion (I)/deletion (D) polymorphism in men with infertility. In a small case series by Balhara et al., the authors highlighted the challenges of oocyte cryopreservation in pre-pubertal girls with haemoglobinopathies. In one of the case reports, the authors report a rare clinical condition of intramyometrial pregnancy in women with diffuse adenomyosis following a frozen embryo transfer. The authors reinforced the need for high clinical suspicion for unusual and rare pregnancy complications following assisted reproduction. In another case report, the authors highlighted the fertility-sparing management of smooth muscle tumour of uncertain malignant potential. In recent months, we have seen a substantial increase in new manuscript submissions. To handle the increase in submissions, we would need more support from our peer reviewers and would like to invite newer reviewers to connect with us. We hope to keep up the momentum and strive for publishing high quality clinically relevant articles in our journal.

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