JAMA

We compared menstrual characteristics and constitutional factors in 268 white women with primary infertility due to endometriosis and in 3,794 white women admitted for delivery at seven collaborating hospitals from 1981 to 1983. Adjusting f…

Endometriosis usually is suspected early in the differential diagnosis of moderate to severe pelvic area pain in premenopausal women. But it also should be considered as a possible cause of low-back and lower-extremity pain as well as of ce…

In 1978, the Food and Drug Administration denied approval of the three-month injectable contraceptive depot medroxyprogesterone acetate for use in the United States. This decision goes against the advice of the FDA's own scientific advisory…

"From the NIH" is prepared and sponsored by the National Institutes of Health to disseminate research findings to physicians. Robert S. Gordon, MD, Editorial Director. For further information: Donald S. Fredrickson, MD, Director, NIH, Bethe…

Combination chemotherapy consisting of hexamethylmelamine and cisplatin, alone or with doxorubicin hydrochloride, was given to 27 patients with advanced ovarian cancer who had disease progression with therapy including alkylating agents. Ei…

CUTANEOUS endometriosis is usually an easily detectable and treatable disease with a favorable prognosis. Although the lesion may occur in skin and subcutaneous tissue not violated by a surgical incision, there are numerous reports of endom…

A 20-year-old single woman suffers from severe dysmenorrhea, unresponsive to analgesic medication. Findings for gynecological examination were normal. Her mother died of mammary cancer at the age of 47. This cancer was diagnosed at age 42 w…

Hysterectomy is indicated for specific diseases of the uterus and for sterilization. Now that modern methods of contraception are available and abortion laws have been liberalized it should be possible in many instances to avoid sterilizati…

Two cases of cyclic sciatica were caused by endometriosis. Both patients gave histories of progressive sciatic pain aggravated at the onset of menses and lasting for several days following menses, but only one had palpable evidence of pelvi…

Since the middle twenties it has been pointed out that ovarian endometriosis may undergo malignant transformation. Long and Taylor,1in 1964, in reviewing 120 cases of primary cancer of the ovary, found several cases of primary ovarian adeno…

Pericardial splenosis has been produced in dogs by a number of investigators. The placement of autogenous slices of spleen on the heart by Leighninger et al 1 resulted in positive takes and increased coronary artery backflow. These investig…

THE PRESENCE of endometrial tissue in the chest is an unusual finding. To the authors' knowledge only ten cases of thoracic endometriosis have been reported. Of these, six were in the pulmonary parenchyma and four others in the pleura. One …

A clinicopathologic study of cutaneous endometriosis in 82 patients includes 28 lesions of the umbilicus, 42 of the lower abdominal wall, and 12 in the inguinal area, labia, and perineum. With the exception of five endometriomas of the ingu…

ALTHOUGH pelvic endometriosis is a relatively common condition, pain resulting from endometriosis but simulating orthopedic conditions is rare. In addition, the problems of diagnosis increase greatly when extrapelvic endometriosis is not as…

ENDOMETRIOSIS IS a condition in which endometrial tissue exists in an ectopic location. Although benign, it may grow and exhibit invasive and metastatic properties as long as ovarian stimulation persists. Symptoms tend to be more severe dur…

ENDOMETRIOSIS may be defined as the occurrence of endometrial-like tissue in locations other than the uterus. There are 3 principal theories regarding the pathogenesis of this disease: embryonic, metaplastic, and migratory.1The first explai…