Is oral contraceptive therapy advisable in woman with family history of breast cancer?

JAMA · 1977 · vol. 238(11) , pp. 1187–8 · PMID:12277755 · W2198922312
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This case report discusses the advisability of oral contraceptive therapy for dysmenorrhea in a woman with a family history of breast cancer, noting limited data on increased cancer risk with oral contraceptive use.

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Abstract

A 20-year-old single woman suffers from severe dysmenorrhea, unresponsive to analgesic medication. Findings for gynecological examination were normal. Her mother died of mammary cancer at the age of 47. This cancer was diagnosed at age 42 while she was taking oral contraceptives. The patient in question, and her 3 sisters, had been warned against taking oral contraceptives. Now it is suggested that her dysmenorrhea might respond to contraceptive therapy. The question is asked regarding the use of oral contraceptives. In response, a diagnostic laparoscopy is recommended to determine if endometriosis is present. If endometriosis is found, medroxyprogesterone acetate may be used for suppression of ovulation, but ovulation may continue to be suppressed for 12-18 months after discontinuing this medication. Danazol is also effective in treating endometriosis and dysmenorrhea but has no estrogenic effect. Available data do not show an increased incidence of mammary cancer in users of oral contraceptives.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Breast Neoplasms Contraceptives, Oral Diagnosis Dysmenorrhea Laparoscopy Contraception Disease Endoscopy Family Planning Services Menstruation Disturbances Neoplasms Physical Examination

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