Summary: A short female with several stigmata of Turner's syndrome was investigated for infertility. She was found to be mosaic for a ring X chromosome and a 45, X cell line in peripheral blood, but skin culture showed only 45, X cells. Gyn…
Danazol is being increasingly used for the treatment of a wide range of disorders, many of which appear to bear little relation to the condition for which the drug was originally marketed--endometriosis. It has been claimed that this drug a…
Summary: Two cases of umbilical endometriosis are reported because of the rarity of the condition and the possible effectiveness of conservative treatment with hormones.
Publications relating to surgical procedures for sterilization have been reviewed, and the incidences of complications and subsequent pregnancies compared. Laparoscopic sterilization has the lowest incidence of complication, the morbidity r…
Multiple sampling was carried out in 4 postmenopausal women for measurement of LH and FSH before and at the end of a 1-week treatment period with Danazol (400 mg daily). A small but significant depression of FSH was found in 3 of 4 subjects…
Fifty-nine patients with ovarian carcinoma were studied with particular reference to abnormalities of the coagulation mechanism. The notable findings were the high incidence of episodic thrombocytosis (73%) and the relation of these peaks o…
Summary: The findings at 100 gynaecological laparoscopics, performed at Hammersmith Hospital, are presented. The procedure was found to present few difficulties, and for the most part permitted accurate diagnosis without exploratory laparot…
Summary The question of the origin of regenerating epithelial cells in the process of metaplasia in the human female genital tract was investigated by setting up a model system in the rat. The uterine lining was injured by the injection of …
Summary: Reference has been made to the theories of origin of endometriosis. Details have been given of a young patient suffering from severe dysmenorrhoea due to haematometra in the rudimentary left horn of a bicornuate uterus with associa…
Summary: An evaluation has been made of the treatment of endometriosis by conservative surgery and by progestogens. In our series of patients, progestogens were given by the intermittent, discontinuous or cyclic method for 20 days every mon…