Between April 1984 and April 1990, 20 patients with a mean age of 27.9 years underwent presacral neurectomy at The Royal Women's Hospital, Melbourne, Australia. Overall, 11 of the 19 patients (58%) assessable for follow-up were totally cure…
A series of 45 ovulatory women with a complaint of menorrhagia were randomized into 3 treatment groups, before receiving therapy with mefenamic acid in 2 cycles and 1 of 3 other agents in 2 cycles: naproxen (group 1; n = 14), a low dose mon…
Hysterectomy in Pakistan, like in other parts of the world is considered to be overused in a number of cases. As a part of a quality assurance process at the Aga Khan University Medical Centre, Karachi, 376 hysterectomies performed between …
To The Editor, Dear Sir Efficacy of Medical Treatment in Infertile Patients with Minimal or Mild Endometriosis Kulenthran Arumugam and Razak M Yusof, Department of Obstetrics and Gynaecology, University of Malaya, 59100 Kuala Lumpur Malaysi…
Spontaneous rupture of pyometra is a rare cause of generalized peritonitis. Only a few cases have been recorded in the English medical literature, most of which were associated with gynaecological malignancy. We have recently treated a pati…
Thirty-two patients with epithelial carcinoma of the ovary underwent a second-look laparotomy after the completion of an average of 18 courses of adjuvant chemotherapy. Nine patients (28%) were found to have persistent disease. This low rat…
Forty-two women with laparoscopically-confirmed pelvic endometriosis (assessed according to the American Fertility Society modified classification) had serum levels of the cell-surface antigen CA-125 measured before, during and after medica…
Ninety-six infertile patients with endometriosis were studied and their endometriosis staged according to the Revised American Fertility Society Classification. Anovulation was detected in 19% of the 32 patients with Stage 1 disease but in …
Three of 5 women who had resection of intramural tubal polyps as part of their infertility treatment conceived normal pregnancies within 12 months. Linear salpingotomy for the resection of polyps may have a place in the surgical management …
Endometriosis involving the ureter is a relatively rare phenomenon but at least 121 cases have been reported previously. The 3 cases presented in this report emphasize some important facets of this condition: the lack of symptoms leading to…
Adenomyosis was noted in 16% of 2,616 consecutive hysterectomy specimens examined during a 7-year period. Multiparas between the ages of 30 and 50 years were most commonly affected. Abnormal uterine bleeding was the common symptom. Myohyper…
A prospective randomized double blind trial, using danazol in a dose of 200 mg twice a day, was carried out on 80 women presenting with severe cyclical symptomatic benign mammary dysplasia. Standardized scores for 4 parameters of disease se…
Serial blood samples have been obtained from 12 patients with ovarian cancer who were treated by surgery and, generally, chemotherapy or radiotherapy. Some achieved clinical remission, but the majority relapsed after variable time interval.…
Catamenial or menses related pneumothorax is a rare clinical manifestation of pulmonary endometriosis. We document a case where the clinical history was the key to diagnosis, and evidence of endometriosis elsewhere was scanty. Prolonged med…
Although the factors involved in the pathophysiology of endometriosis are probably multiple and interrelated, prostaglandins may play an important role in the infertility of women with mild disease. In the present study, prostaglandin F2 al…
Seventy-seven women (median age 30 years, range 21 to 43) underwent microsurgical tubal resections and anastomoses for sterilization-reversal. All patients had a laparoscopy between 8 and 21 days postoperatively to allow early diagnosis and…
There is a need for a predictive test which will assist in the selection of an effective cytotoxic drug and thereby, provide a means of avoiding unnecessary drug-induced toxicity and tumour resistance. In the present study, the viable fract…
Twenty-six women completed a 6-month course of treatment with danazol (at various dosages between 200 and 800 mg daily) for menorrhagia due to dysfunctional uterine bleeding. Objective measurements of menstrual blood loss (MBL) were underta…
Two hundred patients aged 40 years or more who were discharged from hospital with a diagnosis of dysfunctional uterine bleeding were followed up for 6 years. Ninety-three patients eventually underwent hysterectomy and in 64% a pathological …
Endometriosis was induced in 20 rats. Treatment by diathermy was compared to treatment by microsurgical resection of endometrial implants. No significant differences were found between the 2 groups regarding ovulation, nidation index or pre…
The acute effects of retrograde menstruation were studied by endoscopy and cytology. The findings suggest that spillage of menstrual blood into the peritoneal cavity is painful. The technique of making this diagnosis is discussed and the th…