European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Eur J Pharm Sci · ISSN (e) 1879-0720 · 6 papers in corpus
other 2023
doi:10.1016/j.ejps.2023.106501 ·PMID:37339708

Gynaecological health is a neglected field of research that includes conditions such as endometriosis, uterine fibroids, infertility, viral and bacterial infections, and cancers. There is a clinical need to develop dosage forms for gynecolo…

article 2016
doi:10.1016/j.ejps.2016.07.018 ·PMID:27481456

This study was to investigate the effects of cisplatin (CDDP) and letrozole on surgically induced endometriosis and comparison of the two drugs in a rat model. Endometriosis was surgically induced by autologous transplantation of endometria…

article 2016
doi:10.1016/j.ejps.2016.10.031 ·PMID:27989857

Our study investigated poly(lactic-co-glycolic acid) (PLGA) as protein delivery vehicles encapsulate CTLA-4-antibody (anti-CTLA-4) which is essential for CD4+CD25+Treg cells suppressive function exposing superior potential for inhibiting en…

article 2014
doi:10.1016/j.ejps.2014.08.011 ·PMID:25201168

We assessed the efficacy of biodegradable microspheres (MSs) containing nomegestrol acetate (NOMAC) for treatment of endometriosis in a rat model and investigated its preliminary mechanism of action. Sprague-Dawley rats with surgically impl…

article 2013
doi:10.1016/j.ejps.2013.05.021 ·PMID:23747661

Endometriosis is one of the most frequent diseases in gynecology. Currently available medical therapies for this disease are unsatisfactory. Based on current understanding of the pathogenic mechanisms in endometriosis especially the similar…

article 2010
doi:10.1016/j.ejps.2010.01.012 ·PMID:20132884

The objective of this study was to prepare a novel mifepristone-loaded PCL/Pluronic F68 implant to achieve long-term treatment of endometriosis. PCL/Pluronic F68 compound (90/10, w/w) with viscosity average molecular weight of 65,000 was su…