Medical journal of the Islamic Republic of Iran

BACKGROUND: Artificial intelligence (AI) is transforming healthcare with applications that can surpass human performance in prevention, detection, and treatment. This systematic review aimed to collect and assess the impact and success of A…

BACKGROUND: Considering low-quality evidence regarding the impact of laparoscopic surgery on in vitro fertilization (IVF) success rates in women with endometriosis, our research aimed to evaluate IVF success rates and their influential fact…

BACKGROUND: Despite the rapid integration of artificial intelligence (AI) in urological practice, a comprehensive understanding of research evolution and impact patterns remains unexplored. This analysis provides a systematic examination of…

BACKGROUND: Uterine corpus endometrial cancer (UCEC) is known as the sixth most common cancer in the world. Advances in bioinformatics and deep learning have provided the 2 tools for screening large-scale genomic data and discovering potent…

BACKGROUND: Secreted Frizzled Related Protein 4 (sFRP4) is an inflammatory mediator and an antagonist of Wnt signalling, which has been implicated in the pathogenesis of T2DM by causing reduced insulin exocytosis. However, its association w…

BackgroundThe concept of sexual health is used in health promotion, because sexual health is one of the important pillars of human health. Neglecting this aspect of health and its evaluation and measurement can affect the quality of sexual …

BACKGROUND: This study aimed to compare sublingual misoprostol alone or combined with vaginal Isoniazid (INH) for first-trimester abortion. METHODS: In this randomized controlled trial, 80 pregnant women with missed abortion candidates for…

Background: Due to the high prevalence of uterine fibroids or leiomyomas in women of reproductive age and the many treatment options for myomas, finding the best treatment is a challenge for surgeons. Therefore, this study aimed at evaluati…

Background: People's knowledge and attitude play a role in deciding whether or not to use assisted reproductive procedures (ART). There is no information about people's attitudes and awareness about ART in western Iran. Thus, this study was…

Background: Intraabdominal adhesions are associated with an increase in complications during cesarean section because of recurrent cesarean sections. This is why the possibility of predicting adhesions is important. In this study, the diagn…

Background: Lower abdominal or pelvic pain is a common complaint among women and one of the most challenging findings to evaluate. We performed the present study to construct a new algorithm for predicting the chance of ovarian torsion amon…

Background: Detection of pelvic masses is of great value for scheduling a proper treatment process and is an important factor for detection. Frozen section is a diagnostic method for the evaluation of pelvic tumors during surgery. The purpo…

Background: Sexual health education is a controversial issue within the Iranian context. Thus, the present study was conducted to explore the necessity of sex education among young single women and develop and examine the psychometric prope…

Background: Electrosurgery is widely used in reproductive related surgeries and technological advancements to improve efficacy and reduce potential complications. However, some reports have indicated lack of sufficient knowledge and trainin…

Background: Threatened preterm labor (TPL) is the leading cause of hospitalization during pregnancy. Tocolytic agents are the primary therapeutic options for TPL. The aim of this study is to compare intramuscular progesterone with oral nife…

Background: Caesarean section (C-section) is the most common surgery among women worldwide, and the global rate of this surgical procedure has been continuously rising. Hence, it is significantly crucial to develop and apply highly effectiv…

BACKGROUND: Müllerian anomalies are associated with infertility. Hysteroscopy as the gold standard for evaluating Müllerian anomalies is an invasive, expensive and risky procedure which requires enough experience. Transvaginal sonography (T…

BACKGROUND: Release of vascular endothelial growth factor (VEGF) by ovaries in response to HCG administration is one of the main mechanisms of ovarian hyper stimulation syndrome. Since Dopamine/dopamine receptor2 (Dp-r2) pathway activity -m…

Background: Postoperative pain is one of the major problems in patients with femoral or hip fracture. Current study investigates the effect of 0.2% and 0.3% bupivacaine in ultrasound-guided fascia iliaca compartment block (FICB) on postoper…

BACKGROUND: The purpose of the present study was to compare the serum levels of IL6 and CA125 in women with and without endometriosis. They were also compared in mild, moderate and severe cases. METHODS: In this case-control study, CA125 a…

BackgroundDyssynergic defecation is a major cause of chronic functional constipation as a common digestive complaint. We clinically evaluated the effects of biofeedback therapy on the pelvic floor motion indices through magnetic resonance (…

BACKGROUND: To determine the role of Letrozole, an aromatase inhibitor, in the treatment of endometriotic pain. METHODS: In this prospective, randomized, controlled clinical trial in minimally invasive surgery research center, 51 women wit…

BACKGROUND: Delay in diagnosis and treatment of acute appendicitis (AA) results in an increased rate of perforation, postoperative morbidity, mortality and hospital length of stay. Several biochemical parameters including white blood cell (…

Non-Hodgkin lymphoma (NHL) causes many deaths worldwide with increasing incidence. Non-Hodgkin's lymphoma (NHL) may involve the gynecologic tract, and the ovary to be one of the commoner anatomic sites as reported. Ovarian involvement by NH…