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Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study. Figure S1. Ultrasound images of the pelvis. (A) The uterus is enlarged, measuring approximately 59 × 57 × 60 mm, with heterog…
OBJECTIVE: Adenomyosis is a debilitating gynecologic condition. The present study aimed to compare the effects of laparoscopic total hysterectomy (LTH) and high-intensity focused ultrasound (HIFU) on pain relief, menstrual blood loss, and s…
BACKGROUND: Direct comparative data on postoperative sexual function between laparoscopic total hysterectomy (LTH) and high-intensity focused ultrasound (HIFU) in adenomyosis (AM) remain limited; therefore, this retrospective study compared…
Aging impairs the regenerative capacity and differentiation potential of human adipose-derived stem cells (hASCs), but the mechanisms underlying their functional decline remain unclear. Through systematic functional assays and in vivo exper…
ImportanceTonsillectomy has long been scrutinized for its potential long-term impacts on health, with conflicting evidence linking it to increased risks of several diseases, such as cancer, psychiatric disorders, and immune dysfunctions.Obj…
Infertility affects ~1 in 6 people of reproductive age and remains difficult to treat because causes are heterogeneous and diagnostics are incomplete. Recent evidence reframes the female reproductive tract as a low-biomass but biologically …
Acute pancreatitis (AP) is a common inflammatory disease of the pancreas, which can range from mild to severe and life-threatening. The leading causes of AP include gallstones, alcohol abuse, hypertriglyceridemia, trauma, and pancreatic tum…
PURPOSE: Although observational studies suggest a link between socioeconomic status (SES) and hormone-related gynecologic diseases, the causal direction and mediating mechanisms remain unclear. This study aims to explore the causal relation…
Yi Yu,* Zhonghao Mao,* Lianlian Feng, Nannan Li, Xinlin Jiao, Teng Zhang, Baoxia Cui Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, People’s Republic of China*These authors contributed equa…
Supplemental Figure 1. Forest plots demonstrating pool sensitivity and specificity of transvaginal ultrasound in the diagnosis of ureteral endometriosis. Supplemental Figure 2. Summary receiver-operating characteristic curves showing perfor…
Endometriosis (EMs) is an estrogen-dependent chronic inflammatory disease. While apoptosis resistance (evidenced by Bcl-2 upregulation and Bax/caspase-3 downregulation) remains a hallmark of EMs, recent studies reveal a paradoxical coexiste…
ImportancePerfluorobutane sulfonate (PFBS) is a short-chain per- and polyfluoroalkyl substance (PFAS) that has emerged as a significant public health concern due to its widespread environmental contamination and persistent nature. While PFB…
BackgroundCold exposure can induce microvascular damage, which in turn contributes to various gynecological disorders. Liangfang Wenjing Decoction (LFWJD), a classical botanical drug prescription, has long been used to treat gynecological d…
BackgroundAbdominal pregnancy is characterized by the implantation of the gestational sac within the peritoneal cavity, specifically outside the fallopian tubes, ovaries, and cervix. This exceedingly rare form of ectopic pregnancy accounts …
BackgroundPrevious studies have shown that changes in the microbial community of the female urogenital tract are associated with Human papillomavirus (HPV) infection. However, research on this association was mostly focused on a single site…
BACKGROUND: Endometriosis is a gynecological disease that causes severe chronic pelvic pain and infertility in women. The therapeutic efficacy of the traditional herbal combination of Sparganium stoloniferum-Curcuma phaeocaulis (Sangleng-Ez…
We investigated the effect of melatonin on bisphenol A (BPA)-induced oxidative stress damage in testicular tissue and Leydig cells. Mice were gavaged with 50 mg/kg BPA for 30 days, and concurrently, were injected with melatonin (10 mg/kg an…
ObjectivesTo systematically assess the associations between various immune-mediated diseases (IMDs) and human papillomavirus (HPV)-associated diseases.DesignRetrospective cohort study.SettingUK Biobank.ParticipantsA total of 500 371 subject…
Ninjurin 1 (NINJ1) is a double-transmembrane cell-surface protein that might mediate plasma membrane rupture (PMR) and the diffusion of inflammatory factors. PMR is a characteristic of acinar cell injury in severe acute pancreatitis (SAP). …
As one of the most critical economic traits, the litter performance of sows is influenced by their parity. Some studies have indicated a connection between the gut microbiota and the litter performance of animals. In this study, we examined…
Intrauterine adhesion (IUA) is the fibrosis within the uterine cavity. It is the second most common cause of female infertility, significantly affecting women's physical and mental health. Current treatment strategies fail to provide a sati…
BackgroundPatients with Polycystic ovary syndrome (PCOS) experienced endocrine disorders that may present vascular function changes. This study aimed to classify and predict PCOS by radial pulse wave parameters using machine learning (ML) m…