Chune Ren

No ORCID on file · 18 papers in corpus · active 2015-2025

Study types

  • article 11
  • erratum 2
  • preprint 2
  • review 2
  • editorial 1

Condition tags

  • endometriosis 17
  • mesh:D004715 11
  • infertility 6
  • mesh:D004716 1
article 2025
PRMT3-mediated FOXO1 arginine methylation exacerbates oxidative stress-induced decidualization defects in the eutopic endometrium of endometriosis
Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-025-06032-w

Endometriosis is a hormone dependent disease that often accompanies infertility. At present, the incidence rate of endometriosis is on the rise, but its pathogenesis and the mechanism leading to fertility reduction are still unclear. Here, …

article 2024
AURKA Enhances the Glycolysis and Development of Ovarian Endometriosis Through ERβ
Endocrinology ·doi:10.1210/endocr/bqae018

Ovarian endometriosis (EMs) is a benign, estrogen-dependent gynecological disorder. Estrogen receptor beta (ERβ), a nuclear receptor for estradiol, plays an important role in the development of ovarian EMs. Here, we investigated the biologi…

erratum 2024
Correction: Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
Cell death & disease ·doi:10.1038/s41419-024-06613-w
article 2024
NEK2 promotes the development of ovarian endometriosis and impairs decidualization by phosphorylating FOXO1
Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-024-05270-8

Ovarian endometriosis is a common gynecological disease, and one of its most significant symptoms is infertility. In patients with endometriosis, defects in endometrial decidualization lead to impaired endometrial receptivity and embryo imp…

article 2024
PAK5-mediated PKM2 phosphorylation is critical for anaerobic glycolysis in endometriosis
Frontiers of medicine ·doi:10.1007/s11684-024-1069-3
erratum 2023
Correction: CHIP induces ubiquitination and degradation of HMGB1 to regulate glycolysis in ovarian endometriosis
Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-023-04732-9
article 2023
FDX1 enhances endometriosis cell cuproptosis via G6PD-mediated redox homeostasis
Apoptosis : an international journal on programmed cell death ·doi:10.1007/s10495-023-01845-1
article 2023
PFKFB3 promotes endometriosis cell proliferation via enhancing the protein stability of β-catenin
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2023.112083
article 2022
CHIP induces ubiquitination and degradation of HMGB1 to regulate glycolysis in ovarian endometriosis
Cellular and molecular life sciences : CMLS ·doi:10.1007/s00018-022-04637-z
review 2022
Emerging hallmarks of endometriosis metabolism: A promising target for the treatment of endometriosis
Biochimica et biophysica acta. Molecular cell research ·doi:10.1016/j.bbamcr.2022.119381
article 2022
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis
iScience ·doi:10.1016/j.isci.2022.105363

Endometriosis is a common chronic condition characterized by abnormal growth of the endometrium outside the uterus. Heat shock transcription factor 1 (HSF1) is a significant regulator of the proteotoxic stress response and plays an essentia…

article 2022
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
Cell death & disease ·doi:10.1038/s41419-022-05241-6

Endometriosis (EM) is one of the vanquished wonted causes of chronic pelvic sting in women and is closely associated with infertility. The long-term, complex, systemic, and post-treatment recurrence of EM wreaks havoc on women's quality of …

review 2022
Role of inflammatory factors in the etiology and treatment of recurrent implantation failure
Reproductive biology ·doi:10.1016/j.repbio.2022.100698
article 2021
HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-021-00770-9

BACKGROUND: Endometriosis is a chronic hormonal inflammatory disease characterized by the presence of endometrial tissue outside the uterus. Endometriosis often causes infertility, which brings physical and mental pain to patients and their…

preprint 2021
HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression
·doi:10.21203/rs.3.rs-134073/v2

Abstract Background Endometriosis is a chronic hormonal inflammatory disease characterized by the presence of endometrial tissue outside the uterus. Endometriosis often causes infertility, which affects the body and mind of patients and the…

article 2021
PIM2 Promotes Epithelial–Mesenchymal Transition via Phosphorylates β-Catenin in Ovarian Endometriosis
·doi:10.2139/ssrn.3918476
preprint 2020
HSF1 Promotes the Development of Endometriosis by Up-regulating PFKFB3 Expression
·doi:10.21203/rs.3.rs-134073/v1

Abstract Background Endometriosis is a chronic hormonal inflammatory disease characterized by the presence of endometrial tissue (glands and stroma) outside the uterus. Endometriosis seriously affects the physical health of women of childbe…

editorial 2015
Aberrant Gene Regulation in Obstetric, Gynecologic, and Reproductive Diseases
·doi:10.1155/2015/187691

Abnormal gene expression is often detected in various tissues/organs of patients with gynecologic and reproductive diseases. Research efforts on the regulatory mechanisms and molecular pathways will lead to a better understanding of the pat…