Ivo Brosens

Although uterine adenomyoma and endometriosis were described around the turn of the 19th century, the history of the identification of endometriosis has remained controversial and continues to confuse recent literature affecting the managem…

In the early days, all mucosal invasions of abdominal organs were considered to be one pathological condition of uncertain origin, termed adenomyoma. It was only in the 1920s that endometriosis and adenomyosis were clearly separated and it …

Endometriosis is a disease of unknown aetiology, multiple presentations and an enigmatic course during a woman's reproductive years. Clinical aspects of the diagnosis and the rationale for its treatment are discussed.

Modern imaging techniques allow non-invasive diagnosis of adenomyosis, a relatively common disorder characterized by the presence of heterotopic endometrial glands and stroma in the myometrium with hyperplasia of the adjacent smooth muscle.…

BACKGROUND: We postulated that impaired endometrial differentiation in women with pelvic endometriosis predisposes for pre-eclampsia. METHODS: A retrospective case-control study set at the University of Ghent IVF centre. The incidence of p…

However, pioneers of pelvic endoscopy like Raoul Palmer3 in Europe and Edward Diamond4 in the USA continued to promote culdoscopy as the method of choice in at least one special application – the diagnosis of infertility, because it provide…

Although the claim has been made that there are early descriptions of what today we call endometriosis and adenomyosis in theses presented in Europe in the late 17(th) and during the 18(th) centuries, the first description of the condition …

Adenomyosis of the uterus is a common condition amongst women in their reproductive years. It is defined as the presence of heterotopic endometrial glands and stroma in the myometrium with adjacent smooth muscle hyperplasia. The common pres…

This chapter reviews the epidemiological evidence in support of a pathological link and discusses the implications for clinical management. Several epidemiological studies have investigated pregnancy outcome in singleton pregnancy after in …

Although laparoscopy is the gold standard for the diagnosis of endometriosis, the need for this invasive diagnostic tool is a major stumbling-block in both effective clinical management and for research into this common and debilitating dis…

A generalized reproductive dysfunction rather than endometriotic implants is likely to have an impact on the outcome of IVF.

BACKGROUND: The success of IVF treatment is dependent upon embryo quality and coordinated growth and differentiation of the endometrium. Aromatase P450 expression in the human endometrium is thought to be restricted to women with proliferat…

Reproductive performance is now more than ever determining the choice of treatment for each individual couple. The easy access to ART treatments, their financial benefits, and the relative high success rate per cycle are at the basis of a l…