Shoichiro Tsugane

No ORCID on file · 11 papers in corpus
2025
British journal of cancer ·doi:10.1038/s41416-024-02924-z

BackgroundThere are scarce data on risk factors for epithelial ovarian cancer (EOC) in Asian populations. Our goal was to advance knowledge on reproductive -related risk factors for EOC in a large population of Asian women.MethodsThis study…

2020
Nature genetics ·doi:10.1038/s41588-020-0640-3

The overwhelming majority of participants in current genetic studies are of European ancestry. To elucidate disease biology in the East Asian population, we conducted a genome-wide association study (GWAS) with 212,453 Japanese individuals …

article 2015

between cytochrome P450 gene polymorphisms and serum organochlorine TEQ levels in the risk of endometriosis

article 2009
The Science of the total environment ·doi:10.1016/j.scitotenv.2009.09.012

Phthalates may act as an estrogen and are a potential risk factor for estrogen-related diseases such as endometriosis. We assessed the association between phthalate exposure and endometriosis in 166 consecutive women who presented at a univ…

article 2008
The Science of the total environment ·doi:10.1016/j.scitotenv.2008.05.006

Cadmium may act like an estrogen and be a potential risk factor for estrogen-related diseases such as breast cancer and endometriosis. Here, we tested the hypothesis that higher cadmium exposure is associated with endometriosis among infert…

article 2007
Epidemiology (Cambridge, Mass.) ·doi:10.1097/01.ede.0000257571.01358.f9

BACKGROUND: Progression of endometriosis is considered estrogen-dependent. Dietary soy isoflavones may affect the risk of endometriosis, and polymorphisms in estrogen receptor genes may modify this association. We examined associations amon…

article 2007
Molecular human reproduction ·doi:10.1093/molehr/gam018

Exposure to dioxins and polychlorinated biphenyls (PCBs) has been suggested as a possible etiologic factor for endometriosis, but the association remains highly controversial. To assess whether cytochrome P450 (CYP) gene polymorphisms modul…

article 2007
Environmental health and preventive medicine ·doi:10.1007/bf02898033

ObjectivesBisphenol A (BPA), a raw material commonly used in the manufacture of resins such as polycarbonate and epoxy, is a possible xenoestrogen that is hypothesized to disrupt the human endocrine system. Humans are widely exposed to BPA.…

article 2007
·doi:10.1265/ehpm.12.258
other 2005
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.01.130

OBJECTIVE: To explore whether polymorphisms in AhR, ARNT, and AhRR contribute to endometriosis susceptibility and severity. DESIGN: Case control study. SETTING: Hospital. PATIENT(S): One hundred thirty-eight Japanese women with or withou…

article 2005
Environmental research ·doi:10.1016/j.envres.2005.04.003

Endocrine-disrupting chemicals (EDCs) have been proposed as risk factors for endometriosis. Persistent organochlorine compounds, a group of suspected EDCs, are present to some extent in almost all human adipose tissue and blood via the food…