Mircea Onofriescu

Background and Objectives: Endometriosis, a complex and often underdiagnosed gynecological condition, frequently manifests with ovarian involvement, posing significant clinical challenges. Current diagnostic protocols primarily rely on inva…

Association between phenotype and follicle-stimulating hormone (FSH) receptor and FSH beta chain genotype was evaluated in women with ovarian dysfunction. FSH receptor gene single nucleotide polymorphisms (SNPs) were analyzed by restricted …

Endometriosis is a disease very common nowadays affecting 1-2% of the female population, by estrogen-dependent mechanism. The identification of mutations in the gene encoding for the FSH receptor (FSHR) has been reported since 1995. Physiol…

INCIDENCE OF ENDOMETRIOSIS-A MATTER OF PUBLIC CONCERN (Abstract): There is an increasing trend in the incidence of endometriomas, the disease affecting about 5-10% of women of reproductive age. Aim: To determine the incidence of endometrios…

Adenomyosis represents a common gynecological disorder with a negative impact on fertility. In around one third of cases, adenomyosis is completely asymptomatic. We wanted to assess whether the diagnosis of adenomyosis was underestimated. W…

Endometriosis, one of the most common gynecologic pathologies, is defined as an inflammatory, estrogen-dependent disease characterized by the growth of endometrial stroma and glands outside the uterine cavity. It is a multifactorial disease…

Endometriosis is a multifactorial disease that is manifested by infertility and pelvic pain. The purpose of the study was to evaluate the effect of progesterone treatment on the serum level of osteopontin, a multipotent cytokine, in patient…

AIM: The study deals with the preoperative ultrasound diagnosis of ovarian endometriosis, postoperative ultrasound reassessment, laparoscopic surgical resolution of ovarian endometriosis, estimation of recurrence risk 12 months after surger…

The aim of this study (2006–2011) was to assess whether the sonographically detectable morphological alterations of the myometrium induced by adenomyosis changed after insertion of the LNG-IUD. 120 premenopausal symptomatic patients (menorr…

To evaluate the usefulness of ultrasonographic changes patterns after preoperative progestin treatment of endometriosic cysts for the optimal timing of laparoscopic surgery. We did a retrospective study of 250 patients with endometriosic cy…

The aim of this study (2002–2007) was to assess whether the sonographically detectable morphological alterations of the myometrium induced by adenomyosis changed after insertion of the LNG-IUD. Fifty premenopausal symptomatic patients (meno…

Endometrial resection is a well-examined alternative therapy to hysterectomy in the treatment of abnormal uterine bleeding not associated with malignancy, that preserves the uterus at long term in at least 70% of patients. The new devices h…