A J Valentijn

No ORCID on file · 7 papers in corpus · active 2011-2020

Study types

  • article 6
  • other 1

Condition tags

  • endometriosis 7
  • mesh:D004715 5
  • infertility 1
article 2020
Fallopian tube epithelial cells express androgen receptor and have a distinct hormonal responsiveness when compared with endometrial epithelium
Human Reproduction ·doi:10.1093/humrep/deaa177

STUDY QUESTION: How does steroid receptor expression, proliferative activity and hormone responsiveness of the fallopian tube (FT) epithelium compare to that of the endometrial epithelium? SUMMARY ANSWER: Proliferative indices, hormone rece…

article 2018
Abnormally located SSEA1+/SOX9+ endometrial epithelial cells with a basalis-like phenotype in the eutopic functionalis layer may play a role in the pathogenesis of endometriosis
Human Reproduction ·doi:10.1093/humrep/dey336

STUDY QUESTION: Is endometriosis associated with abnormally located endometrial basalis-like (SSEA1+/SOX9+) cells in the secretory phase functionalis and could they contribute to ectopic endometriotic lesion formation? SUMMARY ANSWER: Women…

article 2016
ORIGINAL ARTICLE Gynaecology

SSEA-1 isolates human endometrial basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis

article 2015
Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis
Human Reproduction ·doi:10.1093/humrep/dev267

STUDY QUESTION: How does regulation of telomerase activity (TA) in human endometrial epithelial cells (EEC) by ovarian hormones impact on telomere lengths (TL) and cell proliferation? SUMMARY ANSWER: Healthy endometrial epithelial cell prol…

article 2015
In silico,in vitroandin vivoanalysis identifies a potential role for steroid hormone regulation of FOXD3 in endometriosis-associated genes
Human Reproduction ·doi:10.1093/humrep/dev307

STUDY QUESTION: Can bioinformatics analysis of publically available microarray datasets be utilized in identifying potentially important transcription factors (TF) in the hormonal regulation of the endometrium? SUMMARY ANSWER: Systems integ…

other 2013
SSEA-1 isolates human endometrial basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis
Human Reproduction ·doi:10.1093/humrep/det285

STUDY QUESTION: Can the basal epithelial compartment of the human endometrium be defined by specific markers? SUMMARY ANSWER: Human endometrial epithelial cells from the basalis express nuclear SOX9 and the cell-surface marker SSEA-1, with…

article 2011
Aberrant expression of metastasis-inducing proteins in ectopic and matched eutopic endometrium of women with endometriosis: implications for the pathogenesis of endometriosis
Human Reproduction ·doi:10.1093/humrep/der412

BACKGROUND: Endometriosis is a metastatic disease without obvious tumorigenesis. Expression of S100P, S100A4, osteopontin (OPN) or anterior gradient homologue 2 (AGR2) proteins can induce metastasis but fail to induce tumorigenesis per se. …