Josephine Drury

STUDY QUESTION: What are the effects of pre-analytical variables on the downstream analysis of patient-derived endometrial biopsies? SUMMARY ANSWER: ) in human endometrial biopsies, depending on the pre-analytical variables: disease status …

Table S1. Output from bioinformatics analysis showing differential expression of genes encoding NK cell receptors and ligands in secretory phase endometrium from endometriosis patients when compared with the endometrium of control women wit…

Table S2. The differentially expressed genes in post ovulatory eutopic endometrium of baboons 6 months after induction of endometriosis (n = 4) compared with the same of control animals (n = 4) published in Additional file 3: Table S2, in A…

BACKGROUND: Endometriosis is a common condition associated with growth of endometrial-like tissue beyond the uterine cavity. Previous reports have suggested a role for uNK cells in the pathogenesis of endometriosis postulating that survival…

STUDY QUESTION: Can bioinformatics analysis of publically available microarray datasets be utilized in identifying potentially important transcription factors (TF) in the hormonal regulation of the endometrium? SUMMARY ANSWER: Systems integ…

Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at the blastocyst stage (Group 2). Summary answer: Our data showed that the transfer of frozen blas…

BACKGROUND: In order to test our hypothesis that endometriosis is associated with abnormal expression of telomerase and telomere lengthening in endometrium, we assessed endometrial expression of the human telomerase enzyme and telomere leng…

BACKGROUND: To test our hypothesis that eutopic secretory phase endometrium from women with endometriosis is similar to proliferative phase endometrium from fertile women without endometriosis, we explored the expression of regulators of ce…