Ding Ding

ORCID: 0000-0003-3309-2012 · 31 papers in corpus
lab-animal 2014
Overexpression of lysine-specific demethylase 1 in ovarian endometriomas and its inhibition reduces cellular proliferation, cell cycle progression, and invasiveness
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.11.033

OBJECTIVE: To investigate whether lysine-specific demethylase 1 (LSD1) is aberrantly expressed in endometriomas and whether treatment with tranylcypromine, an LSD1 inhibitor, has any effect on cell viability, cell cycle, and invasiveness. …

lab-animal 2014
Possible Loss of GABAergic Inhibition in Mice With Induced Adenomyosis and Treatment With Epigallocatechin-3-Gallate Attenuates the Loss With Improved Hyperalgesia
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113518984

We have previously reported that induction of adenomyosis in mice results in progressive hyperalgesia, uterine hyperactivity, and elevated plasma corticosterone levels and that epigallocatechin-3-gallate (EGCG) treatment dose dependently su…

lab-animal 2013
Indoleamine 2,3-dioxygenase-1 (IDO1) enhances survival and invasiveness of endometrial stromal cells via the activation of JNK signaling pathway
International journal of clinical and experimental pathology

Evidence for an immunosuppressive function of indoleamine 2,3-dioxygenase (IDO) has been accumulating. However, the unusual distribution of IDO1 in gynecologic cancer cells suggests that modulating immunity may not its only function. To cla…

2012
Endometriosis
·doi:10.1007/978-1-4419-1005-9_14
lab-animal 2012
Inhibition of IDO1 suppresses cyclooxygenase-2 and matrix metalloproteinase-9 expression and decreases proliferation, adhesion and invasion of endometrial stromal cells
Molecular human reproduction ·doi:10.1093/molehr/gas021

Indoleamine 2,3-dioxygenase-1 (IDO1) is an intracellular enzyme that catalyses essential amino acid tryptophan along the kynurenine pathway. The aim of this study was to determine the impact of IDO1 expression on the biological characterist…

2011
KAI1, MMP9 in endometriosis sickness expression and significance
·doi:10.3760/cma.j.issn.1008-1372.2011.11.009

Objective To discuss the expression of tumor shift suppressor gene KAI1,matrix metal proteinase 9 (MMP-9) in endometriosis sickness in dystopia internal membrane and its significance.Methods In 53 patients and 30 healthy controls,the expres…