Seminara S

No ORCID on file · 3 papers in corpus · active 2008-2020
2020
The genetic architecture of sporadic and multiple consecutive miscarriage.
Nature communications ·doi:10.1038/s41467-020-19742-5

Miscarriage is a common, complex trait affecting ~15% of clinically confirmed pregnancies. Here we present the results of large-scale genetic association analyses with 69,054 cases from five different ancestries for sporadic miscarriage, 75…

2018
Large-scale meta-analysis highlights the hypothalamic-pituitary-gonadal axis in the genetic regulation of menstrual cycle length.
Human molecular genetics ·doi:10.1093/hmg/ddy317

The normal menstrual cycle requires a delicate interplay between the hypothalamus, pituitary and ovary. Therefore, its length is an important indicator of female reproductive health. Menstrual cycle length has been shown to be partially con…

2008
Kisspeptin and KISS1R: a critical pathway in the reproductive system.
Reproduction (Cambridge, England) ·doi:10.1530/rep-08-0091

In 2003, three groups around the world simultaneously discovered that KISS1R (GPR54) is a key gatekeeper of sexual maturation in both mice and men. Developmental changes in the expression of the ligand for KISS1R, kisspeptin, support its cr…