Lu J

Background/aimsChronic pancreatitis is an inflammatory disease of the pancreas characterized by progressive tissue destruction and fibrogenesis. The development of chronic pancreatitis is associated with immune cell dysregulation. Currently…

Chronic inflammation is a well-known epidemiologic factor of ovarian clear cell carcinomas (OCCC), but has an uncertain role in prognosis. We developed a systemic inflammation score (SIS) based on preoperative serum albumin and neutrophil-t…

MicroRNA plays an important role in spermatogenesis. Whether pre-miRNAs polymorphisms are associated with idiopathic male infertility remains obscure. In this study, 1378 idiopathic infertile males and 486 fertile controls were included bet…

BACKGROUND: To identify the level of periostin in serum and peritoneal washing fluids (PWF) from women with and without endometriosis, as well as to explore the potential of periostin as a biomarker of endometriosis. METHODS: Samples were o…

ObjectiveTo determine whether emodin facilitates the mesenchymal-epithelial transition (MET) of endometrial stromal cells (ESCs) as well as to explore the mechanism through which emodin favored the MET of ESCs.MethodsCell viability was test…

// Jiaqi Lu 1,* , Xiang Tao 3,* , Jiayi Zhou 2 , Yingying Lu 1 , Zehua Wang 2 , Haiou Liu 2 and Congjian Xu 1,2 1 Department of Gynaecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China 2 Shanghai Key Laboratory of …

The potential role of metformin in treating endometrial cancer remains to be explored. The current study investigated the role of metformin in 17β-estradiol-induced epithelial-mesenchymal transition (EMT) in endometrial adenocarcinoma cells…

Bisphenol A (BPA) is a kind of environmental endocrine disruptors (EEDs) that interfere embryo implantation. Trophoblast invasion plays a crucial role during embryo implantation. In this study, the effects of BPA on invasion ability of huma…

In laparoscopic gynecologic surgery, ultrasound has been typically implemented to diagnose urological and gynecological conditions. We applied laparoscopic ultrasonography (using Esaote 7.5~10MHz laparoscopic transducer) on the retrospectiv…

Gastric cancer is the second most common cause of cancer death worldwide. It is estimated that 5-10% of gastric cancer cases have a familial association; however, knowledge concerning the clinical, pathological features and prognosis to fam…

Published data on the association between the vascular endothelial growth factor (VEGF) gene -460C/T (rs833061), +405G/C (rs2010963), +936T/C (rs3025039) polymorphisms and endometriosis risk are inconclusive. Eleven eligible case-control st…

Clear cell carcinoma of the bladder is a rare tumor of the bladder. There are few reports available on this rare disease, and no cases with recurrence were reported. Here we present a case of 68-year-old woman with primary clear cell carcin…

There are remarkable disparities among patients of different races with prostate cancer; however, the mechanism underlying this difference remains unclear. Here, we present a comprehensive landscape of the transcriptome profiles of 14 prima…

OBJECTIVE: To study the expression of nociceptin in adenomyosis tissue and understand its relationship with the severity of dysmenorrhea. METHODS: The myometrial specimens were collected from 55 patients undergoing hysterectomy at our hospi…

OBJECTIVE: To study the inhibitory effect on the expression of regulated upon activation, normal T cell expressed and secreted (RANTES) and monocyte chemotactic activity of ectopic endometrial stromal cells by nuclear factor (NF)-kappaB dec…

Black cohosh is a commonly used botanical dietary supplement for the treatment of climacteric complaints. Because the opiate system in the brain is intimately associated with mood, temperature, and sex hormonal levels, the activity of black…

OBJECTIVE: To assess the clinical efficacy of uterine arterial embolization (UAE) in the treatment of adenomyosis. METHODS: UAE procedures were performed in 23 patients with adenomyosis. Two 3.0 F FASTRACKER-325 tubes were placed into bilat…

OBJECTIVE: To compare the efficacy and safety of mifepristone and danazol after conservative surgery in the treatment of patients with endometriosis. METHODS: Sixty-one patients with endometriosis (RAFS stage I-IV ) after conservative surge…

OBJECTIVE: To investigate the regulatory effects of mifepristone and progesterone on the secretion of interleukin-6 (IL-6) by endometrial and endometriosis cells in vitro. METHODS: Primary cultures of eutopic and ectopic endometrial cells f…

This study reports on 108 infertile patients with endometriosis diagnosed at laparoscopy. Sixty-four patients had endometriosis and adhesions vaporized with a CO2 laser (LAS) and were prospectively compared with a control group (CON) of 44 …

Five women with endometriosis were given a daily dose of a potent long-acting GnRH agonist, D-Trp6-Pro9-Net-LHRH (GnRH-A) for 28 days in an attempt to suppress ovarian estrogen secretion. The mean level of estradiol (E2) during sampling ove…