Cláudia Scheuer

No ORCID on file · 8 papers in corpus · active 2006-2022

Study types

  • article 8

Condition tags

  • endometriosis 6
article 2022
Indole-3-Carbinol Inhibits the Growth of Endometriotic Lesions by Suppression of Microvascular Network Formation
Nutrients ·doi:10.3390/nu14224940

Endometriosis represents an estrogen-dependent disorder with a complex pathophysiology. Phytochemicals are promising candidates for endometriosis therapy, because they simultaneously target different cellular processes involved in the patho…

article 2022
The ischemic time window of ectopic endometrial tissue crucially determines its ability to develop into endometriotic lesions
Scientific reports ·doi:10.1038/s41598-022-09577-z

Endometriosis develop from shed endometrial fragments via retrograde menstruation. This affects the survival, proliferation and vascularization of the tissue and its final ability to form endometriotic lesions. Within this study, uterine ti…

article 2019
Calligonum comosum (Escanbil) extract exerts anti-angiogenic, anti-proliferative and anti-inflammatory effects on endometriotic lesions
Journal of ethnopharmacology ·doi:10.1016/j.jep.2019.111918

Ethnopharmacological relevanceCalligonum comosum is a desert plant that is applied in traditional folkloric medicine for the treatment of abnormally heavy or prolonged menstruation and menstrual cramps. Moreover, it has been suggested for t…

article 2011
In vitro and in vivo evaluation of the anti‐angiogenic actions of 4‐hydroxybenzyl alcohol
British journal of pharmacology ·doi:10.1111/j.1476-5381.2011.01292.x

BACKGROUND AND PURPOSE: 4-Hydroxybenzyl alcohol (HBA) is a phenolic plant compound, which has been shown to influence many cellular mechanisms. In the present study, we analysed in vitro and in vivo the anti-angiogenic actions of this pleio…

article 2010
Melatonin Impairs Fracture Healing by Suppressing RANKL-Mediated Bone Remodeling
·doi:10.1016/j.jss.2010.08.036

BackgroundMelatonin, the major pineal hormone, is known to regulate distinct physiologic processes. Previous studies have suggested that it supports skeletal growth and bone formation, most probably by inhibiting bone resorption. There is n…

article 2008
Epigallocatechin-3-gallate inhibits estrogen-induced activation of endometrial cells in vitro and causes regression of endometriotic lesions in vivo
Human Reproduction ·doi:10.1093/humrep/den245

BACKGROUND: Epigallocatechin-3-gallate (EGCG), the major component of green tea, is a pleiotropic substance, which may inhibit tumor growth via multiple intracellular signaling pathways. Herein, we studied whether EGCG may also be effective…

article 2006
Rapamycin induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation
British journal of pharmacology ·doi:10.1038/sj.bjp.0706857

BACKGROUND AND PURPOSE: Rapamycin is a widely used drug with antifungal, immunosuppressant and antiangiogenic effects. Herein, we studied whether immunosuppressive doses of rapamycin are capable of influencing endometriotic lesions. EXPERIM…

article 2006
Selective cyclo-oxygenase-2 inhibition induces regression of autologous endometrial grafts by down-regulation of vascular endothelial growth factor-mediated angiogenesis and stimulation of caspase-3-dependent apoptosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.05.068

ObjectiveTo investigate the effects of selective cyclo-oxygenase-2 (COX-2) inhibition on the angiogenesis and proliferation of endometrial grafts.DesignIntravital fluorescence microscopic study.SettingInstitute for Clinical and Experimental…