J J Brosens

Pregnancy is dependent upon the endometrium acquiring a receptive phenotype that facilitates apposition, adhesion and invasion of a developmentally competent embryo. Surface-enhanced laser desorption/ionization time-of-flight mass spectrome…

The fetal endometrium becomes responsive to steroid hormones around the fourth month of pregnancy starting with an oestrogenic phase, which is followed late in pregnancy by a secretory phase. Based on post-mortem studies, the endometrium at…

The pathogenesis of early-onset endometriosis has recently been revisited, sparked by the discovery of endometrial stem/progenitor cells and their possible role in endometriosis, and because maternal pregnancy hormone withdrawal following d…

OBJECTIVE: To review the role of laparoscopy in the management of chronic pelvic pain (CPP). METHOD: A literature search was conducted to obtain a clear perspective on the role of laparoscopy for CPP. RESULTS: Laparoscopy has been widely …

OBJECTIVE: To review the role of laparoscopy in the management of chronic pelvic pain (CPP). METHOD: A literature search was conducted to obtain a clear perspective on the role of laparoscopy for CPP. RESULTS: Laparoscopy has been widely us…

Human non-gravid myometrium differentiates in response to ovarian sex steroids into a subendometrial layer or junctional zone and an outer myometrial layer. Compared to the outer myometrial layer, the junctional zone myocytes are characteri…

OBJECTIVE: To evaluate prospectively the role of endovaginal ultrasonography in the diagnosis of adenomyosis and to identify predictive characteristics. SETTING: In Vitro Fertilisation Unit, Hammersmith Hospital. SUBJECTS: Fifty-six women w…