Zhang JV

No ORCID on file · 7 papers in corpus · active 2018-2025

Study types

  • article 3
  • preprint 1

Condition tags

  • endometriosis 4
  • chronic_pelvic_pain 1
  • infertility 1
2025
Low-dose letrozole-HMG regimen reverses letrozole-induced endometrial impairment and improves frozen embryo transfer outcomes.
Frontiers in cell and developmental biology ·doi:10.3389/fcell.2025.1725350

IntroductionLetrozole monotherapy, while effective for ovulation induction, may compromise endometrial receptivity in frozen embryo transfer (FET) cycles due to estrogen suppression. This study aimed to compare the FET outcomes and analyze …

article 2025
TGF-β/snail-mediated epithelial-to-mesenchymal transition disrupts estradiol metabolism through suppressing the HSD17B2 expression in endometriotic epithelial cells
Biochemical and biophysical research communications ·doi:10.1016/j.bbrc.2025.151964

Endometriosis affects nearly 10 % of reproductive-age women and is characterized by the growth of endometrial-like tissues outside the uterus. This disease poses significant diagnostic and therapeutic challenges due to its unknown origins a…

2025
TGF-β/Snail-mediated epithelial-to-mesenchymal transition disrupts estradiol metabolism through suppressing the HSD17B2 expression in endometriotic epithelial cells
Biochemical and biophysical research communications

Endometriosis affects nearly 10% of reproductive-age women and is characterized by the growth of endometrial-like tissues outside the uterus. This disease poses significant diagnostic and therapeutic challenges due to its unknown origins an…

2022
Chemerin: A Functional Adipokine in Reproductive Health and Diseases.
Biomedicines ·doi:10.3390/biomedicines10081910

As a multifaceted adipokine, chemerin has been found to perform functions vital for immunity, adiposity, and metabolism through its three known receptors (chemokine-like receptor 1, CMKLR1; G-protein-coupled receptor 1, GPR1; C-C motif chem…

article 2022
Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression
Frontiers in pharmacology ·doi:10.3389/fphar.2022.985618

Endometriosis is a common gynecological disease, characterized by the presence of endometrial-like lesions outside the uterus. This debilitating disease causes chronic pelvic pain and infertility with limited therapeutics. Chemerin is a sec…

preprint 2021
Bioinspired Long-Wavelength Excitable Near-Infrared AIEdots for Endometriosis Targeting and Image-Guided Surgery
·doi:10.26434/chemrxiv.14131775.v1

Endometriosis（EM）is a non-cancerous and intractable disease in clinic due to the ambiguity of its etiology and mechanism. Surgical removal of the lesions is more efficient method for EM treatment compared with pharmacological intervention. …

article 2018
The Clinical and Experimental Research on the Treatment of Endometriosis with Thiostrepton
Anti-cancer agents in medicinal chemistry ·doi:10.2174/1871520618666180108100211

BACKGROUND/OBJECTIVE: Forkhead Box M1 (FOXM1) is frequently activated in tumors. We studied the expression and the possible mechanism of FOXM1 and evaluated the effects of thiostrepton in an endometriotic rat model. METHODS AND MATERIAL: Th…