Trapphoff T

No ORCID on file · 3 papers in corpus · active 2022-2024
2024
Scientific reports ·doi:10.1038/s41598-024-60251-y

Smoking of classic cigarettes has been well-established as a health risk factor, including cardiovascular, neurological, and pulmonary diseases. Adverse effects on human reproduction have also been shown. Smokers are assumed to have a signi…

2024
Cells ·doi:10.3390/cells13171497

Expression of the double homeobox 4 (DUX4) transcription factor is highly regulated in early embryogenesis and is subsequently epigenetically silenced. Ectopic expression of DUX4 due to hypomethylation of the D4Z4 repeat array on permissive…

2022
Aging ·doi:10.18632/aging.203891

An age-dependent increase in ribosomal DNA (rDNA) methylation has been observed across a broad spectrum of somatic tissues and the male mammalian germline. Bisulfite pyrosequencing (BPS) was used to determine the methylation levels of the r…