Smoking of classic cigarettes has been well-established as a health risk factor, including cardiovascular, neurological, and pulmonary diseases. Adverse effects on human reproduction have also been shown. Smokers are assumed to have a signi…
Expression of the double homeobox 4 (DUX4) transcription factor is highly regulated in early embryogenesis and is subsequently epigenetically silenced. Ectopic expression of DUX4 due to hypomethylation of the D4Z4 repeat array on permissive…
An age-dependent increase in ribosomal DNA (rDNA) methylation has been observed across a broad spectrum of somatic tissues and the male mammalian germline. Bisulfite pyrosequencing (BPS) was used to determine the methylation levels of the r…
Im Rahmen der Sterilitätsabklärung wird Endometriose 3–10-mal häufiger beobachtet als in Kollektiven fertiler Frauen. Abgesehen von Zuständen mit offensichtlicher tubarer Komponente ist derzeit unklar, ob die Fertilitätseinschränkung bei un…
PurposeTo determine whether the concentration of hyaluronan (HA) in follicular fluid predicts implantation success following embryo transfer.MethodsFollicular fluids from 170 IVF patients were tested by ELISA for HA concentration.ResultsThe…
To determine the effect of ovarian endometriomas on in vitro fertilization (IVF) outcome, two groups of patients were studied. Group I consisted of seven patients with ovarian endometriomas and severe pelvic adhesions treated for a total of…