Keeney GL

No ORCID on file · 9 papers in corpus · active 2000-2016

Study types

  • article 3
  • other 1

Condition tags

  • endometriosis 3
  • infertility 1
article 2016
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719116671218

Abnormal uterine bleeding (AUB), a common health concern of women, is a heterogeneous clinical entity that is traditionally categorized into organic and nonorganic causes. Despite varied pharmacologic treatments, few offer sustained efficac…

2016
Gynecologic Oncology ·doi:10.1016/j.ygyno.2016.02.023

BackgroundIt is unclear whether the transcriptional subtypes of high grade serous ovarian cancer (HGSOC) apply to high grade clear cell (HGCCOC) or high grade endometrioid ovarian cancer (HGEOC). We aim to delineate transcriptional profiles…

2015
Oncotarget ·doi:10.18632/oncotarget.5927

Ovarian cancer represents the most lethal tumor type among malignancies of the female reproductive system. Overall survival rates remain low. In this study, we identify the serine protease inhibitor Kazal type 1 (SPINK1) as a potential ther…

other 2014
Endocrinology ·doi:10.1210/en.2014-1139

Endocrine regulation of uterine biology is critical for embryo receptivity and human reproduction. Uterine endometrium depends on extrinsic sex steroid input and hence likely has mechanisms that enable adaptation to hormonal variation. Emer…

article 2013
PloS one ·doi:10.1371/journal.pone.0060165

Endometriosis affects approximately 10% of young, reproductive-aged women. Disease associated pelvic pain; infertility and sexual dysfunction have a significant adverse clinical, social and financial impact. As precise disease etiology has …

2013
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology ·doi:10.1158/1055-9965.epi-13-0391

BackgroundOvarian carcinoma is composed of five major histologic types, which associate with outcome and predict therapeutic response. Our aim was to evaluate histologic type assessments across the centers participating in the Ovarian Tumor…

2013
Nature communications ·doi:10.1038/ncomms2629

HNF1B is overexpressed in clear cell epithelial ovarian cancer, and we observed epigenetic silencing in serous epithelial ovarian cancer, leading us to hypothesize that variation in this gene differentially associates with epithelial ovaria…

2012
Gynecologic Oncology ·doi:10.1016/j.ygyno.2011.12.444

ObjectiveTo estimate the incidence of synchronous endometrial cancer (EC) and ovarian cancer (OC) in the female population, among all women with EC, and in women under 50 years of age with EC, and to identify factors associated with synchro…

article 2000
Gynecologic oncology ·doi:10.1006/gyno.2000.5905

ObjectiveEndometriosis is extremely common in developed countries. Obesity is a major health concern and may cause hyperestrogenism. Hormonal replacement, particularly unopposed estrogens after hysterectomy, is becoming popular. Because end…