Akemi Koshiba

ORCID: 0000-0001-8066-666X · 41 papers in corpus · active 2015-2025

Study types

  • article 30
  • other 4
  • preprint 2
  • review 2
  • letter 1

Condition tags

  • endometriosis 35
  • mesh:D004715 25
  • endometrioma 11
  • adenomyosis 6
  • infertility 3
  • mesh:D004412 2
  • chronic_pelvic_pain 2
  • die_deep_infiltrating 2
  • dysmenorrhea 2
  • dyspareunia 1
other 2025
Human Reproduction ·doi:10.1093/humrep/deaf054

STUDY QUESTION: Does the restoration of regulatory T cells (Tregs) suppress the progression of endometriosis? SUMMARY ANSWER: Adoptive transfer of Tregs suppresses the progression of endometriosis and reduces the levels of helper T (Th)-ce…

erratum 2024
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2024.02.004

The authors regret “We are very sorry for the careless printing mistake in the proper alignment of case numbers in Table 2, Table 3 of the mentioned article. These case numbers [(n = 25) and (n = 782)] should be read above the line and belo…

other 2024
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2023.12.033

OBJECTIVE: We examined the prevalence and risk factors in association with neonatal uterine bleeding (NUB) by retrospective search of contemporary and historical medical records and investigated the possible association between the history …

article 2023
Free radical biology & medicine ·doi:10.1016/j.freeradbiomed.2023.10.402

Menstrual blood, containing high iron levels, can undergo retrograde transport into the abdominal cavity. Excess iron causes oxidative stress and inflammation. Iron metabolism is regulated by hepcidin, and serum hepcidin levels are increase…

article 2023
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-023-01099-1

BACKGROUND: It has been hypothesized that the origin of early-onset endometriosis could be from endometrial mesenchymal stem cells (eMSCs) in neonatal uterine blood (NUB). There is no information on the possible mechanistic basis linking an…

article 2023
Gynecology and minimally invasive therapy ·doi:10.4103/gmit.gmit_132_22

Objectives: The effects of laparoscopic surgical management in women with stage III/IV endometriosis remain controversial. The standard extent of resection for stage III/IV endometriosis with deep endometriosis to treat endometriosis-associ…

preprint 2022
·doi:10.21203/rs.3.rs-1951340/v2
preprint 2022
·doi:10.21203/rs.3.rs-1951340/v1
article 2022
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2022.07.009
article 2022
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-022-01089-5
article 2022
·doi:10.2139/ssrn.4201389
article 2022
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgac118

CONTEXT: Progesterone resistance including progesterone receptor (PR) deficiency contributes to the pathophysiology of endometriosis; however, whether the PR expression levels in ovarian endometrioma (OE) correlate with the postoperative re…

article 2021
Human Reproduction ·doi:10.1093/humrep/deab090

STUDY QUESTION: Is there any change in the distribution of microvilli and microtubules in the apical endometria of women with adenomyosis? SUMMARY ANSWER: We observed microvilli damage in the apical endometria and an axonemal alteration cha…

article 2021
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13498

PROBLEM: Despite abundant reports on the risk role of uterine outflow tract obstruction in endometriosis, information on the occurrence of endometriosis in women with Chlamydia trachomatis infection causing fallopian tube obstruction is unk…

other 2021
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2021.07.014

OBJECTIVE: We examined the hypothesis that antibiotic treatment with or without gonadotropin releasing hormone agonist (GnRHa) may decrease intrauterine infection with consequent decrease in tissue inflammation, cell proliferation and angio…

article 2021
Reproductive medicine and biology ·doi:10.1002/rmb2.12421

Abstract Purpose Human adenomyosis has an adverse effect on female fertility. Exact mechanistic basis is still unclear. We investigated the occurrence of chronic endometritis (CE) in different types of human adenomyosis. Methods This is a p…

article 2020
European journal of obstetrics & gynecology and reproductive biology: X ·doi:10.1016/j.eurox.2020.100108

Chronic inflammation in endometriosis is associated with increased risk of future cardiovascular disease; however, no studies have investigated the cardiovascular risk of women who have undergone hormonal therapy for endometriosis. We inves…

article 2020
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.13380

PROBLEM: Inflammation and immune responses play crucial roles in the development of endometriosis. Although interleukin-9 (IL-9) has a pro-inflammatory function in chronic inflammatory diseases, its function in endometriosis remains unknown…

letter 2020
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgaa541
article 2020
International journal of surgery protocols ·doi:10.1016/j.isjp.2020.02.003

BACKGROUND: The Vagi-Pipe® is a useful device for performing a total laparoscopic hysterectomy. The conventional model of the Vagi-Pipe® is unable to grasp the uterus during colpotomy for recovery of the resected uterus. However, the modifi…

article 2019
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2019.01.011
article 2019
Reproductive biomedicine online ·doi:10.1016/j.rbmo.2019.03.210
article 2019
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2019-00350

CONTEXT: Regulatory T (Treg) cells and T-helper-17 (Th17) cells may be involved in endometriosis. Information on the pattern of change in the percentages of Treg and Th17 cells in the peripheral blood (PB) and peritoneal fluid (PF) of women…

review 2019
Reproductive medicine and biology ·doi:10.1002/rmb2.12285

BACKGROUND: It has been well established that endometriosis is an estrogen-dependent disease. Although the exact pathogenesis of the disease is still unclear, it is known to be characterized by estrogen-dependent growth and maintenance of t…

article 2019
Human Reproduction ·doi:10.1093/humrep/dez067

STUDY QUESTION: Is a peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α)-mediated pathway involved in the development of endometriosis? SUMMARY ANSWER: PGC-1α plays critical roles in inflammation and cell proliferation of e…