Fraser HM

No ORCID on file · 11 papers in corpus · active 1982-2009

Study types

  • review 5
  • article 4

Condition tags

  • endometriosis 8
  • dysmenorrhea 1
  • infertility 1
  • dyspareunia 1
review 2009
Reproduction, fertility, and development ·doi:10.1071/rd08272

The marked cyclical physiological angiogenesis in the developing follicle, corpus luteum and endometrium implies a critical role in health and disease. Our approach to understanding its regulation has been to localise and quantify the tempo…

review 2000
British medical bulletin ·doi:10.1258/0007142001903364

The rapid, controlled and cyclical nature of angiogenesis in the female reproductive tract suggests that interference with this process should provide a novel approach to manipulation of reproductive function. Many factors involved in the r…

article 1992
Clinical endocrinology ·doi:10.1111/j.1365-2265.1992.tb02908.x

OBJECTIVE: The duration of action of a gonadotrophin releasing hormone (GnRH) agonist implant designed to be effective for 3 months was investigated in women by monitoring drug release and ovarian hormone secretion. Serum inhibin secretion …

article 1990
Fertility and Sterility ·doi:10.1016/s0015-0282(16)53217-8

Ten endometriosis patients received luteinizing hormone releasing hormone (LH-RH) agonist (buserelin) implant injections (6.6 mg subcutaneously) at days 0, 42, 84 and 126. Serum LH and follicle-stimulating hormone (FSH) were lowered by day …

review 1989
BMJ (Clinical research ed.) ·doi:10.1136/bmj.298.6672.475
review 1987
Bailliere's clinical endocrinology and metabolism ·doi:10.1016/s0950-351x(87)80052-6

What is the current state of clinical application of inhibition of gonadal activity with LHRH agonists or antagonists? It seems unlikely in the short term that antagonists will be widely applied due to the short-acting nature of the present…

review 1986
Progress in clinical and biological research
article 1985
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem-60-3-579

The effect of continuous administration of an LHRH agonist for 14 days on follicular estradiol secretion was studied in adult female stumptailed macaque monkeys. The infusion was started either during the early follicular phase or during th…

1984
British medical journal (Clinical research ed.) ·doi:10.1136/bmj.289.6454.1267
article 1983
British medical journal (Clinical research ed.) ·doi:10.1136/bmj.287.6406.1667

An agonist analogue of luteinising hormone releasing hormone (buserelin) was successfully used to treat women with endometriosis. A dose of 200 micrograms administered intranasally thrice daily was found to be effective in five patients, in…

1982
British medical journal (Clinical research ed.) ·doi:10.1136/bmj.285.6347.990