Manuela Neri

Background/Objectives: Endometriosis and high-grade serous ovarian cancer (HGS-OC) share common features within the peritoneal immune microenvironment, yet they exhibit divergent clinical outcomes. This study aimed to dissect the immune–met…

INTRODUCTION: Endometriosis is a chronic disease characterized by endometriotic cells implanted outside the uterus triggering a chronic inflammatory state. Estradiol stimulates the endometriotic implants, which overexpress estrogen receptor…

Abstract Ultrasound is a readily available, non-invasive and low cost screening for the identification of endometriosis lesions, but its diagnostic specificity strongly depends on the experience of the operator. For this reason, computer-ai…

Surgery for benign gynecologic conditions may lead to infertility complications. In a cross-sectional study we investigated depressive and anxiety symptoms, Quality of Life (QoL), and coping strategies in women with benign gynecologic condi…

OBJECTIVE: To analyze the reproducibility of ultrasonographic (US) findings of rectosigmoid endometriosis among examiners with different level of expertise using stored three-dimensional (3D) volumes of the posterior compartment of the pelv…

The aim of this study was to compare the accuracy of seven classical machine learning (ML) models trained with ultrasound (US) soft markers to raise suspicion of endometriosis of uterosacral ligaments. Input data to the models was retrieved…

Ultrasound is an effective tool to detect and characterize endometriosis lesions. Variances in endometriosis lesions' appearance and distorted anatomy secondary to adhesions and fibrosis present as major difficulties during the complete son…

The aim of this study was to evaluate the use of ultrasound (US) soft markers to raise suspicion of uterosacral involvement in women suspected of having deep endometriosis. We included in this prospective observational study all patients wi…

In the present pictorial we show the ultrasonographic appearances of endometriosis in atypical sites. Scar endometriosis may present as a hypoechoic solid nodule with hyperechoic spots while umbilical endometriosis may appear as solid or pa…

The aim of this study was to evaluate the use of ultrasound (US) soft markers as a first-line imaging tool to raise suspicion of forniceal involvement in women suspected of having deep endometriosis. We included in this prospective observat…

To analyse the reproducibility of ultrasonographic (US) findings of rectosigmoid endometriosis among examiners with different level of expertise using stored 3D volumes of posterior compartment of the pelvis as a part of SANABA (Sardinia-Na…

The aim of this study was to evaluate the incidence of deep endometriosis in patients without suspicion of endometrioma using an imaging technique as ultrasonography (US). We included in this observational study all patients with less than …

the aim of this study was to compare the accuracy of seven classical machine learning models of ultrasound (US) soft markers in raising suspicion of bowel involvement using a dataset with previously published results. The data driven strate…

According to the theory of retrograde menstruation, endometriosis would be due to the existence of Müllerian anomalies (MA) causing obstruction of the menstruation outflow tract. The aim of the present study to describe endometriosis findin…

Uterine fibroids (UFs) are the most common gynaecological benign disease. Even though often asymptomatic, UFs can worsen women's health and their quality of life, causing heavy bleeding and anaemia, pelvic discomfort and reduced fertility. …

This observational study was conducted in premenopausal women who presented themselves at the Obstetrics and Gynecology Department of the University Hospital of Cagliari (Italy), for heavy menstrual bleeding (HMB) dependent on uterine myoma…

INTRODUCTION: Suppression of sex-steroid secretion is required in a variety of gynecological conditions. This can be achieved using gonadotropin releasing hormone (GnRH) agonists that bind pituitary gonadotropin receptors and antagonize the…

In the menopausal transition (MT), combined oral contraceptive (COC) should be chosen accordingly to its neutrality on liver metabolism and to its ability to counter the increase of fat mass (FM) that occurs in this reproductive period of l…